NR0B2 抗体 (Middle Region)
-
- 抗原 See all NR0B2 抗体
- NR0B2 (Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2))
-
抗原表位
- Middle Region
-
适用
- 人, 大鼠, 兔, 犬, 马, 豚鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This NR0B2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- AEAPVPSILK KILLEEPSSS GGSGQLPDRP QPSLAAVQWL QCCLESFWSL
- 预测反应
- Dog: 100%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Rabbit: 100%, Rat: 79%
- 产品特性
- This is a rabbit polyclonal antibody against NR0B2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human NR0B2
- Top Product
- Discover our top product NR0B2 Primary Antibody
-
anti-Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2) (AA 110-159) antibody
NR0B2 适用: 人, 兔, 犬, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2) (AA 1-257) antibodyNR0B2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2) (AA 1-257) antibodyNR0B2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A11 unconjugated
anti-Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2) antibodyNR0B2 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2) (AA 56-83) antibodyNR0B2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB29166 unconjugated
anti-Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2) (AA 1-260) antibodyNR0B2 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2) antibodyNR0B2 适用: 人, 大鼠, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2) antibodyNR0B2 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2) (Ligand Binding Domain) antibodyNR0B2 适用: 人, 小鼠, 兔, 猴, Hamster IHC, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2) antibodyNR0B2 适用: 人, 大鼠, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 257 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- NR0B2 (Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2))
- 别名
- NR0B2 (NR0B2 产品)
- 别名
- SHP antibody, SHP1 antibody, SHP-1 antibody, Shp1 antibody, Shp antibody, NR0B2-A antibody, Nr0b2 antibody, SHP-A antibody, gb:bc058069 antibody, nuclear receptor subfamily 0 group B member 2 antibody, nuclear receptor subfamily 0, group B, member 2 antibody, nuclear receptor subfamily 0, group B, member 2a antibody, NR0B2 antibody, Nr0b2 antibody, nr0b2a antibody
- 背景
-
NR0B2 is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. It is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function.The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: SHP, SHP1
Protein Interaction Partner: TP53, SMAD4, IL3RA, HNRNPA1, FN1, PEF1, RBP5, ZMYND10, CHRD, ZAP70, RXRA, PLSCR1, Nr1i3, EID1, NR5A2, ESRRG, MDM2, RNF31, UBC, HDAC3, HDAC1, GPS2, SIN3A, EHMT2, TRAF6, SMARCA2, SNW1, VDR, RARG, PPARD, HNF4G, HNF4A, ESRRA, RUNX2, Prmt5, SIRT6, SIRT7, SIRT1
Protein Size: 257 - 分子量
- 28 kDa
- 基因ID
- 8431
- NCBI登录号
- NM_021969, NP_068804
- UniProt
- Q15466
- 途径
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
-
