BRD4 抗体 (Bromodomain Containing 4) (C-Term)

Details for Product anti-BRD4 Antibody No. ABIN2780921, 供应商: Log in to see
抗原
  • brd4-b
  • BRD4
  • fb18g03
  • wu:fb18g03
  • CAP
  • HUNK1
  • HUNKI
  • MCAP
  • Brd5
  • WI-11513
  • bromodomain containing 4
  • brd4
  • BRD4
  • Brd4
抗原表位
C-Term
23
17
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15
11
8
8
3
3
2
2
1
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠
106
38
20
7
6
6
6
5
4
2
1
1
宿主

101
5
1
克隆类型
多克隆
标记
This BRD4 antibody is un-conjugated
7
7
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
应用范围
Chromatin Immunoprecipitation (ChIP), Immunofluorescence (IF), Western Blotting (WB)
74
50
48
35
27
24
5
4
3
2
1
选项
Supplier
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Supplier Product No.
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免疫原 The immunogen is a synthetic peptide directed towards the C terminal region of human BRD4
Blocking Peptide Blocking peptide for this product available: ABIN973879
序列 EIEIDFETLK PSTLRELERY VTSCLRKKRK PQAEKVDVIA GSSKMKGFSS
预测反应 Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
产品特性 This is a rabbit polyclonal antibody against BRD4. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
别名 BRD4 (BRD4 Antibody 摘要)
背景 BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting.The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15,19)(q13,p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Alias Symbols: CAP, HUNKI, MCAP, HUNK1
Protein Interaction Partner: AFF1, CDK9, CCNT1, STAT3, JMJD6, TCERG1, HEXIM1, RN7SK, PRPF40A, vif, RPL6, MYC, MLLT1, ELAVL1, SUMO2, UBC, YWHAZ, KAT8, C8orf33, MESDC2, HIST1H4A, HIST1H3A, YWHAE, MED1, EP300, KDM5B, C7orf25, CHFR, CLDN1, RFC1, RFC4, HIST2H3C, HIST2H4A, MED12, MED24, ME
Protein Size: 722
分子量 80 kDa
基因ID 23476
NCBI登录号 NM_014299, NP_055114
途径 Chromatin Binding
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 722 AA

限制 仅限研究用
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
厂商提供的图像
Immunofluorescence (IF) image for anti-Bromodomain Containing 4 (BRD4) (C-Term) antibody (ABIN2780921) Sample Type: HeLa
Primary Antibody Dilution: 4 µg/mL
Secondary Antibody: ...
Chromatin Immunoprecipitation (ChIP) image for anti-Bromodomain Containing 4 (BRD4) (C-Term) antibody (ABIN2780921) Chromatin Immunoprecipitation (ChIP) Using BRD4 Antibody - C-terminal region (ARP3907...
背景 Schweiger, You, Howley: "Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function." in: Journal of virology, Vol. 80, Issue 9, pp. 4276-85, 2006 (PubMed).

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