(3 references)-
- 抗原 See all FCER2 抗体
- FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FCER2 antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS), ELISA
- 品牌
- BD Pharmingen™
- 产品特性
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The M-L233 antibody reacts with the low affinity receptor for human IgE, FcεRII/CD23. CD23 is a type II membrane protein which can be expressed by B cells, monocytes, macrophages, eosinophils, platelets, and dendritic cells. CD23 can mediate IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. Soluble CD23 (sCD23) can be released by CD23+ cells as a result of proteolytic cleavage of membrane CD23. Larger fragments of sCD23 (e.g., 37-25 kDa) retain their IgE-binding capacity whereas smaller fragments (i.e., ≤ 12 kDa) do not. Soluble CD23 may have immunoregulatory effects on the growth and differentiation of B cells and other cell types. Profile of peripheral blood lymphocytes analyzed on a FACScan
BD Pharmingen™ Biotin Mouse Anti-Human CD23 - Biotin - Clone M-L233 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.5 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- M
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product FCER2 Primary Antibody
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anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) antibody
FCER2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 151-321) antibodyFCER2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 150-330) antibodyFCER2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) antibodyFCER2 适用: 人, 小鼠, 大鼠 IF, IHC (p) 宿主: 小鼠 Monoclonal 2F2 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 48-321) antibodyFCER2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal FCER2-3592 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-321) antibodyFCER2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal S52 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-321) antibodyFCER2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal S51 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-321) antibodyFCER2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A7 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 48-321) antibodyFCER2 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 48-321) antibodyFCER2 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-023M unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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: "Membrane expression of Fc epsilon RII/CD23 and release of soluble CD23 by follicular dendritic cells." in: Advances in experimental medicine and biology, Vol. 329, pp. 393-8, (1993) (PubMed).
: "Fc epsilon RII/CD23: the low affinity receptor for IgE." in: Annual review of immunology, Vol. 8, pp. 623-45, (1990) (PubMed).
: "The use of avidin-biotin interaction in immunoenzymatic techniques." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).
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: "Membrane expression of Fc epsilon RII/CD23 and release of soluble CD23 by follicular dendritic cells." in: Advances in experimental medicine and biology, Vol. 329, pp. 393-8, (1993) (PubMed).
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- 抗原
- FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
- 别名
- CD23 (FCER2 产品)
- 别名
- BLAST-2 antibody, CD23 antibody, CD23A antibody, CLEC4J antibody, FCE2 antibody, IGEBF antibody, Fcer2a antibody, Fc fragment of IgE receptor II antibody, FCER2 antibody, Fcer2 antibody
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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