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GPR56 抗体 (PE-Cy7)

GPR56 适用: 人 FACS 宿主: 小鼠 Monoclonal CG4 PE-Cy7
产品编号 ABIN2659352
发货至: 中国
  • 抗原 See all GPR56 抗体
    GPR56 (G Protein-Coupled Receptor 56 (GPR56))
    适用
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    宿主
    • 35
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    小鼠
    克隆类型
    • 38
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    单克隆
    标记
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    This GPR56 antibody is conjugated to PE-Cy7
    应用范围
    • 32
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
    克隆位点
    CG4
    亚型
    IgG1 kappa
    Top Product
    Discover our top product GPR56 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    GPR56 (G Protein-Coupled Receptor 56 (GPR56))
    别名
    GPR56 (GPR56 产品)
    别名
    fc49b10 antibody, wu:fc49b10 antibody, BFPP antibody, TM7LN4 antibody, TM7XN1 antibody, Cyt28 antibody, GPR56 antibody, adhesion G protein-coupled receptor G1 antibody, G protein-coupled receptor 56 antibody, ADGRG1 antibody, adgrg1 antibody, Adgrg1 antibody, GPR56 antibody
    背景
    GPR56, also known as TM7XN1, is an orphan G-protein-coupled receptor (GPCR) containing seven transmembrane domains and a mucin-like domain in the N-terminal region. The total length of the human GPR56 gene is approximately 15 kb, and it consists of 13 exons and encodes 693 amino acids. GPR56 is expressed in a wide range of tissues, such as brain, thyroid gland, and heart. Mutations in human GPR56 gene were found to cause a specific brain malformation called bilateral frontoparietal polymicrogyria. Recently, GPR56 was found specifically expressed on cytotoxic NK and T lymphocytes, including CD8+, CD4+, and γδ T cells, which might affect the migratory properties of these cells. GPR56 was also found significantly downregulated in some cancer cells, suggesting that it may play a role in growth suppression and cancer metastasis.
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