GPR56 产品
(G Protein-Coupled Receptor 56 (GPR56))
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This gene encodes a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
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Featured GPR56 Categories
Recommended GPR56 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (4)
Cat. No.
ABIN522766
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN1048840
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN6258204
Quantity
100 μL
Datasheet
Datasheet
Recommended GPR56 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6385567
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4883128
Quantity
96 tests
Datasheet
Datasheet
Recommended GPR56 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355626
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1788443
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
Cat. No.
ABIN7491385
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our GPR56 Products
: "Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 19, pp. 6194-9, (2015) (PubMed).: "GPR56 inhibits melanoma growth by internalizing and degrading its ligand TG2." in: Cancer research, Vol. 74, Issue 4, pp. 1022-31, (2014) (PubMed).
: "Disease-associated GPR56 mutations cause bilateral frontoparietal polymicrogyria via multiple mechanisms." in: The Journal of biological chemistry, Vol. 286, Issue 16, pp. 14215-25, (2011) (PubMed).
: "The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity." in: The Journal of biological chemistry, Vol. 286, Issue 33, pp. 28914-21, (2011) (PubMed).
Synonyms and alternative names related to GPR56
adhesion G protein-coupled receptor G1 (ADGRG1), adhesion G protein-coupled receptor G1 (adgrg1), adhesion G protein-coupled receptor G1 (Adgrg1), G protein-coupled receptor 56 (GPR56), BFPP, Cyt28, fc49b10, GPR56, TM7LN4, TM7XN1, wu:fc49b10Protein level used designations for GPR56
- G protein-coupled receptor 56
- G-protein coupled receptor 56-like
- 7-transmembrane protein with no EGF-like N-terminal domains-1
- G-protein coupled receptor 56
- secretin receptor
- serpentine receptor cyt28
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