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GPR77 产品

(G Protein-Coupled Receptor 77 (GPR77))

Categories

This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012].

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Featured GPR77 Categories

GPR77 抗体

High quality antibodies with extensive validation data.

GPR77 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

GPR77 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GPR77 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7139743
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7245095
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN1048365
Quantity 50 μg
Datasheet Datasheet

Recommended GPR77 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1124566
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1124567
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1124568
Quantity 96 tests
Datasheet Datasheet

Recommended GPR77 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355632
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3107828
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3125358
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our GPR77 Products

A Verghese, Demir, Chun, Fribourg, Cravedi, Llaudo, Woodruff, Yadav, Lira, Medof, Heeger: "T Cell Expression of C5a Receptor 2 Augments Murine Regulatory T Cell (TREG) Generation and TREG-Dependent Cardiac Allograft Survival." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 6, pp. 2186-2198, (2018) (PubMed).

Karsten, Wiese, Mey, Figge, Woodruff, Reuter, Scurtu, Kordowski, Almeida, Briukhovetska, Quell, Sun, Ender, Schmudde, Vollbrandt, Laumonnier, Köhl: "Monitoring C5aR2 Expression Using a Floxed tdTomato-C5aR2 Knock-In Mouse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 9, pp. 3234-3248, (2017) (PubMed).

Croker, Halai, Kaeslin, Wende, Fehlhaber, Klos, Monk, Cooper: "C5a2 can modulate ERK1/2 signaling in macrophages via heteromer formation with C5a1 and β-arrestin recruitment." in: Immunology and cell biology, Vol. 92, Issue 7, pp. 631-9, (2014) (PubMed).

Roy, Paglialunga, Schaart, Moonen-Kornips, Meex, Phielix, Hoeks, Hesselink, Cianflone, Schrauwen: "Relationship of C5L2 receptor to skeletal muscle substrate utilization." in: PLoS ONE, Vol. 8, Issue 2, pp. e57494, (2013) (PubMed).

Bamberg, Mackay, Lee, Zahra, Jackson, Lim, Whitfeld, Craig, Corsini, Lu, Gerard, Gerard: "The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction." in: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7633-44, (2010) (PubMed).

Synonyms and alternative names related to GPR77

complement component 5a receptor 2 (C5AR2), complement component 5a receptor 2 (C5ar2), C5L2, E030029A11Rik, GPF77, GPR77, Gpr77

Protein level used designations for GPR77

  • G protein-coupled receptor 77
  • G protein-coupled receptor C5L2
  • C5a anaphylatoxin chemotactic receptor 2
  • C5a anaphylatoxin chemotactic receptor C5L2
  • G-protein coupled receptor 77
  • C5A receptor beta
  • complement 5A receptor beta
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