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TIAL1 抗体 (C-Term)

TIAL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 马, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN184155
发货至: 中国
  • 抗原 See all TIAL1 抗体
    TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))
    抗原表位
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 26
    • 14
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 兔, 马, 斑马鱼, 豚鼠
    宿主
    • 21
    • 4
    • 1
    克隆类型
    • 24
    • 2
    多克隆
    标记
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TIAL1 antibody is un-conjugated
    应用范围
    • 13
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB)
    序列
    WNQQGFGVDQ SPSAAWMGGF GAQPPQGQAP PPVIPPPNQA GYGMASYQTQ
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 85%, Zebrafish: 76%
    产品特性
    This is a rabbit polyclonal antibody against TIAL1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human TIAL1
    Top Product
    Discover our top product TIAL1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 375 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))
    别名
    TIAL1 (TIAL1 产品)
    别名
    TCBP antibody, TIAR antibody, 5330433G13Rik antibody, AL033329 antibody, mTIAR antibody, zgc:66130 antibody, tcbp antibody, tiar antibody, TIA1 cytotoxic granule associated RNA binding protein like 1 antibody, Tia1 cytotoxic granule-associated RNA binding protein-like 1 antibody, TIA1 cytotoxic granule-associated RNA binding protein-like 1 antibody, TIAL1 antibody, Tial1 antibody, tial1 antibody
    背景
    The protein encoded by TIAL1 is a member of a family of RNA-binding proteins and possesses nucleolytic activity against cytotoxic lymphocyte target cells. The gene product is a cytotoxic granule-associated protein and has been shown to bind specifically to poly(A) homopolymers and to fragment DNA in permeabilized target cells. It has been suggested that members of this protein family may be involved in the induction of apoptosis. One isoform contains a lysosome-targeting motif in its C-terminal auxiliary domain, however, alternative splicing results in a T-cluster DNA-binding isoform, differing at the C-terminus where a hydrophobic sequence replaces the lysosome-targeting motif.
    Alias Symbols: TCBP, TIAR
    Protein Interaction Partner: SUMO2, UBC, RPA3, RPA2, RPA1, BMI1, SOX2, MAPK1, GADD45A, VCAM1, ITGA4, FN1, MRPL53, SARNP, UFM1, SBDS, MRPS28, TOMM40, ACAA2, GNB2L1, SF3B4, SCAMP3, SCO2, ALDH5A1, VDAC1, UBE2D2, THY1, SOD1, MBNL1, CAND1, DCUN1D1, COPS5, COPS6, CUL1, CUL2, CUL3, CUL4A, C
    Protein Size: 375
    分子量
    42 kDa
    基因ID
    7073
    NCBI登录号
    NM_003252, NP_003243
    UniProt
    Q01085
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