TIAL1 抗体
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- 抗原 See all TIAL1 抗体
- TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))
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适用
- 人, 小鼠, Non-Human Primate
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TIAL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- Anti-TIAR Purified
- 特异性
- The mouse monoclonal antibody 6E3 recognizes TIAR, an ubiquitously expressed approximately 42 kDa intracellular RNA-binding protein.
- 纯化方法
- Purified by protein-A affinity chromatography.
- 免疫原
- GST-tagged recombinant human TIAR
- 克隆位点
- 6E3
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product TIAL1 Primary Antibody
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anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) antibody
TIAL1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (AA 266-375) antibodyTIAL1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (AA 1-252) antibodyTIAL1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (AA 1-90) antibodyTIAL1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (Internal Region) antibodyTIAL1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (Internal Region) antibodyVerified TIAL1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (AA 9-277) antibodyTIAL1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (C-Term) antibodyTIAL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 马, 斑马鱼, 小鸡, 豚鼠, Bat, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (AA 275-325) antibodyTIAL1 适用: 人, 小鼠 IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Flow cytometry: Intracellular staining, recommended dilution: 5 μg/mL
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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- 抗原
- TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))
- 别名
- TIAR (TIAL1 产品)
- 别名
- TCBP antibody, TIAR antibody, 5330433G13Rik antibody, AL033329 antibody, mTIAR antibody, zgc:66130 antibody, tcbp antibody, tiar antibody, TIA1 cytotoxic granule associated RNA binding protein like 1 antibody, Tia1 cytotoxic granule-associated RNA binding protein-like 1 antibody, TIA1 cytotoxic granule-associated RNA binding protein-like 1 antibody, TIAL1 antibody, Tial1 antibody, tial1 antibody
- 背景
- TIA1 cytotoxic granule associated RNA binding prot,TIAR is an ubiquitously expressed RNA-binding protein, which regulates translational control, splicing, and other activities, including apoptosis. TIAR attenuates CDK1 activity, and is essential for the G2/M checkpoint. It accumulates in nuclear foci in late G2 phase and prophase in cells under replication stress. In steady state TIAR shuttles between the cytoplasm and the nucleus, probably as a part of nucleocytoplasmic transport of mRNA, but under stress conditions it accumulates mRNA molecules in granules and prevents their translation. Nucleolytic activity of TIAR against attacked target cells of cytotoxic lymphocytes has also been reported. Similarly, e.g. in permeabilized thymocytes TIAR triggers DNA fragmentation.,TCBP, TIAL1
- 基因ID
- 7073
- UniProt
- Q01085
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