DEAF1 抗体 (C-Term)
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- 抗原 See all DEAF1 抗体
- DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 豚鼠, 犬, 马, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DEAF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- TGCHKVNYCS TFCQRKDWKD HQHICGQSAA VTVQADEVHV AESVMEKVTV
- 预测反应
- Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 93%, Rat: 79%
- 产品特性
- This is a rabbit polyclonal antibody against DEAF1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human DEAF1
- Top Product
- Discover our top product DEAF1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 565 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
- 别名
- DEAF1 (DEAF1 产品)
- 别名
- AU042387 antibody, C230009B13Rik antibody, NUDR antibody, SPN antibody, ZMYND5 antibody, MYND5 antibody, spn antibody, DEAF1 antibody, nudr antibody, zmynd5 antibody, CG8567 antibody, DEAF-1 antibody, Deaf-1 antibody, Dmel\\CG8567 antibody, deaf1 antibody, l(3)76BDv antibody, deformed epidermal autoregulatory factor 1 (Drosophila) antibody, DEAF1, transcription factor antibody, DEAF1 transcription factor antibody, deformed epidermal autoregulatory factor 1 homolog antibody, Deformed epidermal autoregulatory factor-1 antibody, Deaf1 antibody, DEAF1 antibody, LOC509260 antibody, deaf1 antibody, deaf-1 antibody
- 背景
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DEAF1 down-regulates transcription of those genes by binding to sequence with multiple copies of TTC[CG]G present in their own promoter and that of the HNRPA2B1 gene. DEAF1 binds to the retinoic acid response element (RARE) AGGGTTCACCGAAAGTTCA. DEAF1 activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase.
Alias Symbols: SPN, NUDR, ZMYND5
Protein Interaction Partner: IRF7, IRF3, CREB1, PELI1, PELI2, HRSP12, GSK3B, GSK3A, CDKN2A, PPP1CC, PPP1CA, CDC37, AIMP2, TK1, RAD23B, PIN1, HRAS, FHL1, CDKN1A, ASCC2, INTS1, LMO4, DEAF1,
Protein Size: 565 - 分子量
- 59 kDa
- 基因ID
- 10522
- NCBI登录号
- NM_021008, NP_066288
- UniProt
- O75398
- 途径
- Tube Formation
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