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DEAF1 抗体

DEAF1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7243235
发货至: 中国
  • 抗原 See all DEAF1 抗体
    DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
    适用
    • 52
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    宿主
    • 62
    • 6
    克隆类型
    • 63
    • 5
    多克隆
    标记
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    This DEAF1 antibody is un-conjugated
    应用范围
    • 57
    • 34
    • 13
    • 6
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    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human DEAF1
    亚型
    IgG
    Top Product
    Discover our top product DEAF1 Primary Antibody
  • 应用备注
    IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.4 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
    别名
    DEAF1 (DEAF1 产品)
    别名
    AU042387 antibody, C230009B13Rik antibody, NUDR antibody, SPN antibody, ZMYND5 antibody, MYND5 antibody, spn antibody, DEAF1 antibody, nudr antibody, zmynd5 antibody, CG8567 antibody, DEAF-1 antibody, Deaf-1 antibody, Dmel\\CG8567 antibody, deaf1 antibody, l(3)76BDv antibody, deformed epidermal autoregulatory factor 1 (Drosophila) antibody, DEAF1, transcription factor antibody, DEAF1 transcription factor antibody, deformed epidermal autoregulatory factor 1 homolog antibody, Deformed epidermal autoregulatory factor-1 antibody, Deaf1 antibody, DEAF1 antibody, LOC509260 antibody, deaf1 antibody, deaf-1 antibody
    背景
    Suppressin, also known as DEAF1 (deformed epidermal autoregulatory factor 1), SPN, NUDR (nuclear DEAF-1-related transcriptional regulator), or ZMYND5 (zinc finger MYND domain-containing protein 5), is a transcription factor required for embryonic development. Suppressin contains one SAND domain and one C-terminal MYND-type zinc finger. It interacts with LMO4 and CLIM-2, suggesting that it plays a role mediating cell fate and embryonic pattern formation. Suppressin is expressed in a variety of tissues and localizes to the nucleus. Several isoforms exist due to alternative splicing and, depending on the isoform, Suppressin is secreted in some cell types. Secreted Suppressin can function to inhibit cell proliferation, arresting cells in the G0 or G1 phase. Mutations in the gene encoding Suppressin may result in a growth advantage leading to the development and progression of neoplasia. This suggest that Supressin is a potential target for cancer therapy.
    NCBI登录号
    NP_066288
    UniProt
    O75398
    途径
    Tube Formation
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