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CD11c 抗体

ITGAX 适用: 小鼠 FACS, IP 宿主: 大鼠 Monoclonal 223H7 unconjugated
产品编号 ABIN1449276
发货至: 中国
  • 抗原 See all CD11c (ITGAX) 抗体
    CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
    适用
    • 164
    • 54
    • 13
    • 12
    • 10
    • 9
    • 9
    • 5
    • 1
    小鼠
    宿主
    • 115
    • 52
    • 18
    • 14
    • 4
    大鼠
    克隆类型
    • 154
    • 44
    • 2
    单克隆
    标记
    • 75
    • 16
    • 16
    • 14
    • 12
    • 7
    • 5
    • 5
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    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
    This CD11c antibody is un-conjugated
    应用范围
    • 123
    • 49
    • 48
    • 47
    • 35
    • 29
    • 19
    • 13
    • 6
    • 5
    • 4
    • 3
    • 2
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    • 1
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    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP)
    特异性
    This antibody reacts with mouse CD11c.
    纯化方法
    Protein G agarose
    免疫原
    Murine DC from C57BL/6 mice
    克隆位点
    223H7
    亚型
    IgG2a
    Top Product
    Discover our top product ITGAX Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原
    CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
    别名
    CD11c (ITGAX 产品)
    别名
    CD11C antibody, SLEB6 antibody, RGD1561123 antibody, AI449405 antibody, Cd11c antibody, Cr4 antibody, N418 antibody, integrin subunit alpha X antibody, integrin alpha X antibody, ITGAX antibody, Itgax antibody
    背景
    The CD11c (alpha X integrin, ~150 kDa) glycoprotein non-covalently associates with CD18 (beta2 integrin, ~95 kDa) to form the heterodimeric complement receptor type 4 (CR4), which is involved in monocyte/granulocyte adhesion during inflammatory responses. The CD11c/CD18 receptor binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions. CD11c/CD18 is also implicated in B cell proliferation and mediates B cell binding to fibrinogen. CD11c is commonly used as a marker for dendritic cells, but it is also expressed on macrophages, monocytes, granulocytes, NK cells, activated T and B lymphocytes and microglia.Synonyms: CD11 antigen-like family member C, ITGAX, Integrin alpha-X, Leu M5, Leukocyte adhesion glycoprotein p150 95 alpha chain, Leukocyte adhesion receptor p150 95
    基因ID
    16411
    NCBI登录号
    NP_067309
    UniProt
    Q9QXH4
    途径
    Complement System, Activated T Cell Proliferation, Integrin Complex
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