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FKBP8 抗体

FKBP8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN127298
发货至: 中国
  • 抗原 See all FKBP8 抗体
    FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))
    适用
    • 49
    • 34
    • 25
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 60
    • 5
    • 1
    克隆类型
    • 61
    • 4
    多克隆
    标记
    • 29
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FKBP8 antibody is un-conjugated
    应用范围
    • 53
    • 25
    • 14
    • 14
    • 11
    • 6
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB)
    特异性
    The antibody recognizes a ~40 kDa band of FKBP38.
    纯化方法
    Protein A chromatography
    免疫原
    Synthetic peptide surrounding amino acid 344 of mouse FKBP38
    Top Product
    Discover our top product FKBP8 Primary Antibody
  • 应用备注
    Western Blot: 0.5 - 4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    BPS containing 0.1 % BSA, 20 % glycerol, and 0.02 % thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))
    别名
    FKBP8 / FKBP38 (FKBP8 产品)
    别名
    FKBP8 antibody, fkbp8 antibody, 38kDa antibody, FKBP-38 antibody, FKBP-8 antibody, Fkbp38 antibody, zgc:77672 antibody, FKBP38 antibody, FKBPr38 antibody, FK506 binding protein 8 antibody, FK506 binding protein 8 L homeolog antibody, FKBP8 antibody, fkbp8 antibody, Fkbp8 antibody, fkbp8.L antibody
    背景
    FK506-binding protein 38 (FKBP38), a member of the immunophilin family, has been implicated to play an important role in apoptosis through its involvement in the mechanism that targets Bcl-2 and Bcl-xL to the outer mitochondrial membrane (OMM). Suppression of endogenous FKBP38 by RNAi or transfection of a mutant FKBK38 missing the transmembrane domain necessary for mitochondrial insertion, resulted in the translocation of Bcl-2 and Bcl- xL from the OMM to the cytosol. It has also been suggested that FKBP38 may play a role in the cross-talk between the Bcl-2 and the Calcineurin/NF-AT apoptosis signaling pathways and in cell size regulation through interactions with tuberous sclerosis genes.Synonyms: 38 kDa FK506-binding protein, FK506-binding protein 8, Peptidyl-prolyl cis-trans isomerase FKBP8, Rotamase
    基因ID
    23770
    NCBI登录号
    NP_036313
    UniProt
    Q14318
    途径
    Autophagy
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