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HDAC5 抗体

HDAC5 适用: 人, 小鼠, 大鼠 WB, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN127240
发货至: 中国
  • 抗原 See all HDAC5 抗体
    HDAC5 (Histone Deacetylase 5 (HDAC5))
    适用
    • 79
    • 58
    • 43
    • 33
    • 28
    • 18
    • 12
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 77
    • 2
    克隆类型
    • 77
    • 2
    多克隆
    标记
    • 49
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This HDAC5 antibody is un-conjugated
    应用范围
    • 70
    • 25
    • 24
    • 22
    • 22
    • 18
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    特异性
    The antibody detects ~124 kDa histone deacetylase 5. It does not cross-react with other HDAC proteins including HDAC1, 2, 3, 4, 6, 7, and 8.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse and Rat (Weak).
    纯化方法
    Affinity Chromatography
    免疫原
    Synthetic peptide surrounding amino acid 575 of Human HDAC-5
    Top Product
    Discover our top product HDAC5 Primary Antibody
  • 应用备注
    Western Blot: 1 μg/mL. Immunoprecipitation: 20 μg/mL. Immunohistochemistry: 20 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS, pH 7.2, 0.01 % Thimerosal, 0.5 % BSA, 30 % Glycerol
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原
    HDAC5 (Histone Deacetylase 5 (HDAC5))
    别名
    HDAC5 (HDAC5 产品)
    别名
    HD5 antibody, NY-CO-9 antibody, AI426555 antibody, Hdac4 antibody, mHDA1 antibody, mKIAA0600 antibody, ATHDA5 antibody, HDA5 antibody, MAF19.7 antibody, MAF19_7 antibody, histone deacetylase 5 antibody, histone deacetylase 5 antibody, HDAC5 antibody, Hdac5 antibody, HDA05 antibody, hdac5 antibody
    背景
    HDAC5 is a member of the class II mammalian histone deacetylase family, which is structurally related to yeast HDA1. Human HDAC5 is composed of 1122 amino acid residues. The deacetylase domain of HDAC5 is located at the C-terminal half of the molecule. The N-terminal non-deacetylase domain does not show any significant homology with any published sequence. Both domains are required for HDAC5-mediated repression of gene transcription. HDAC5 interacts with a growing number of transcriptional factors including MEF2A as well as other HDAC proteins. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions.Synonyms: Antigen NY-CO-9, HD5, Histone deacetylase 5, KIAA0600
    基因ID
    10014
    NCBI登录号
    NP_001015053
    UniProt
    Q9UQL6
    途径
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process
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