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HDAC5 抗体

HDAC5 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7254941
发货至: 中国
  • 抗原 See all HDAC5 抗体
    HDAC5 (Histone Deacetylase 5 (HDAC5))
    适用
    • 78
    • 57
    • 42
    • 33
    • 28
    • 18
    • 12
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 76
    • 2
    克隆类型
    • 76
    • 2
    多克隆
    标记
    • 48
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This HDAC5 antibody is un-conjugated
    应用范围
    • 70
    • 25
    • 23
    • 22
    • 21
    • 18
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human HDAC5 (NP_005465.2).
    亚型
    IgG
    Top Product
    Discover our top product HDAC5 Primary Antibody
  • 应用备注
    IHC 1:50-1:200 IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    HDAC5 (Histone Deacetylase 5 (HDAC5))
    别名
    HDAC5 (HDAC5 产品)
    背景
    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
    基因ID
    10014
    UniProt
    Q9UQL6
    途径
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process
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