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FLT1 抗体 (Extracellular Domain)

Name: FLT1 抗体 (Extracellular Domain)
SKU: ABIN115152
Availability: OutOfStock

FLT1 适用: 人, 小鼠 WB, IP, IF, EIA 宿主: 小鼠 Monoclonal FLTEWF unconjugated

产品编号 ABIN115152

发货至: 中国

Datasheet as PDF

抗原 See all FLT1 抗体

FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
抗原表位
16

12

11

11

7

7

7

5

4

4

4

4

4

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Extracellular Domain
适用
143

65

65

12

3

2

2

2

2

1

1

1

1

1

1

1
人, 小鼠
宿主
141

31

3

1
小鼠
Compatible Secondaries
克隆类型
142

34
单克隆
标记
92

22

11

5

5

5

5

5

5

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This FLT1 antibody is un-conjugated
应用范围
110

49

44

36

22

22

21

15

14

13

8

4

4

2

1

1

1
Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

特异性

The monoclonal antibody will recognize recombinant and naturally occurring form of Human VEGFR-1/Flt-1.

交叉反应（详细）

Species reactivity (tested):Human, Mouse.

纯化方法

Affinity Chromatography on Protein G

免疫原

Recombinant Human soluble extracellular Flt-1 protein (D5) (Cat.-No DA3539)

克隆位点

FLTEWF

亚型

IgG1

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anti-Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 1100-1200) antibody
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anti-Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) antibody
FLT1 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 1-687) antibody
FLT1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 1251-1338) antibody
FLT1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated

anti-Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) antibody
FLT1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB16736 unconjugated

anti-Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (pTyr1048) antibody
FLT1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 18-308) antibody
FLT1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA (1.5-8 μg/mL), Western blotting (1-10 μg/mL), Immunoprecipitation (1-5 μg/mL lysateor reaction volume).
Other applications not tested.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
溶解方式

Restore with distilled sterile water to a concentration of 0.1-1.0 mg/mL.

缓冲液

PBS pH 7.4 containing no preservative

储存液

Without preservative

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

别名

VEGFR-1 / Flt-1 (FLT1 产品)

别名

FLT antibody, FLT-1 antibody, VEGFR-1 antibody, VEGFR1 antibody, FLT1 antibody, flt1b antibody, sFlt1 antibody, AI323757 antibody, Flt-1 antibody, fms related tyrosine kinase 1 antibody, FMS-related tyrosine kinase 1 antibody, vascular endothelial growth factor receptor 1 antibody, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) antibody, FMS-like tyrosine kinase 1 antibody, vascular endothelial growth factor receptor-1 antibody, FLT1 antibody, Flt1 antibody, CpipJ_CPIJ012087 antibody, flt1 antibody, FLT-1 antibody

背景

Endothelial cells express three different vascular endothelial growth factor (VEGF) receptors, belonging to the family of receptor tyrosine kinases (RTKs). They are named VEGFR-1 (Flt-1), VEGFR-2 (KDR/Flk-1), VEGFR-3 (Flt-4). Their expression is almost exclusively restricted to endothelial cells, but VEGFR-1 can also be found on monocytes, dendritic cells and on trophoblast cells. The flt-1 gene was first described in 1990. The receptor contains seven immunoglobulin-like extracellular domains, a single transmembrane region and an intracellular splited tyrosine kinase domain. Compared to VEGFR-2 the Flt-1 receptor has a higher affinity for VEGF but a weaker signaling activity. VEGFR-1 thus leads not to proliferation of endothelial cells, but mediates signals for differentiation. Interestingly a naturally occuring soluble variant of VEGFR-1 (sVEGFR-1) was found in HUVE supernatants in 1996, which is generated by alternative splicing of the flt-1 mRNA.Synonyms: FLT, FLT1, FRT, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, VEGF Receptor 1, VEGFR1, Vascular endothelial growth factor receptor 1, Vascular permeability factor receptor

基因ID

2321

NCBI登录号

NP_001153392

UniProt

P17948

途径

RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals