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ACE2 抗体 (C-Term)

Name: ACE2 抗体 (C-Term)
SKU: ABIN113168
Availability: OutOfStock

ACE2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

产品编号 ABIN113168

发货至: 中国

Datasheet as PDF

抗原 See all ACE2 抗体

ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
抗原表位
16

14

12

9

9

9

6

5

5

4

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 788-805, C-Term
适用
143

54

47

6

5

1

1

1

1

1

1
人
宿主
130

20

6
兔
Compatible Secondaries
克隆类型
109

47
多克隆
标记
81

16

10

8

5

4

3

3

3

3

3

3

3

3

1

1

1

1

1

1

1

1
This ACE2 antibody is un-conjugated
应用范围
123

68

50

36

36

19

17

11

11

11

10

6

3

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

特异性

Reacts with Human Angiotensin Converting Enzyme 2 (ACE2, SARS Receptor) C-terminal, amino acids 788 to 805. Does not crossreact with ACE1.

纯化方法

Immunoaffinity

免疫原

Synthetic peptide corresponding to amino acids 788 to 805 of human ACE2 (Genbank accession NP_068576).

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anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 601-700) antibody
ACE2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) antibody
ACE2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal AC18F unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-250) antibody
ACE2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) antibody
ACE2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 93-464) antibody
ACE2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 392-739) antibody
ACE2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (N-Term) antibody
Verified ACE2 适用: 人 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) antibody
ACE2 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM47 unconjugated Recombinant Antibody

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 773-805) antibody
ACE2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 140-172) antibody
ACE2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Suitable for use in Western blot (0.5 to 2 μg/mL). Human kidney or human testis cell lysatecan be used as positive control and a 90 kDa band can be detected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

0.5mg/mL

缓冲液

PBS containing 0.02 % Sodium azide as preservative.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
抗原

ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

别名

ACE2 (ACE2 产品)

别名

ACE1 antibody, CD143 antibody, DCP antibody, DCP1 antibody, ICH antibody, MVCD3 antibody, ACEH antibody, 2010305L05Rik antibody, zgc:92514 antibody, angiotensin I converting enzyme antibody, angiotensin I converting enzyme 2 antibody, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 antibody, ACE antibody, ACE2 antibody, Ace2 antibody, ace2 antibody

背景

Angiotensin converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1 7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function. ACE1 inhibitors such as catopril and lisinopril do not block ACE2 activity. The full length sequence for ACE2 encodes an 805 amino acid protein with predicted mass of 92.46 kDa and a pI of 5.22.Synonyms: ACE-related carboxypeptidase, Angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog

基因ID

59272

NCBI登录号

NP_068576

UniProt

Q9BYF1

途径

ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour