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Cyclin D2 抗体

CCND2 适用: 人, 小鼠 WB, IF 宿主: 小鼠 Monoclonal CY-D2 unconjugated
产品编号 ABIN1106875
发货至: 中国
  • 抗原 See all Cyclin D2 (CCND2) 抗体
    Cyclin D2 (CCND2)
    适用
    • 97
    • 51
    • 39
    人, 小鼠
    宿主
    • 77
    • 24
    小鼠
    克隆类型
    • 80
    • 21
    单克隆
    标记
    • 51
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    • 2
    • 2
    • 2
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    This Cyclin D2 antibody is un-conjugated
    应用范围
    • 77
    • 40
    • 20
    • 17
    • 14
    • 13
    • 13
    • 10
    • 8
    • 8
    • 4
    • 2
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    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    This antibody reacts to Cyclin D2.
    纯化方法
    Affinity chromatography
    免疫原
    Recombinant human cyclin D2 protein
    克隆位点
    CY-D2
    亚型
    IgG2a
    Top Product
    Discover our top product CCND2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1.2 % sodium acetate or neutral PBS
    浓度
    0,1 mg/mL
    缓冲液
    1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Cyclin D2 (CCND2)
    别名
    Cyclin D2 (CCND2 产品)
    别名
    si:ch211-240j22.2 antibody, ccnd2 antibody, CCND2 antibody, kiak0002 antibody, zgc:162280 antibody, LOC100224096 antibody, KIAK0002 antibody, BF642806 antibody, C86853 antibody, Vin-1 antibody, Vin1 antibody, cD2 antibody, 2600016F06Rik antibody, AI256817 antibody, cyclin D2, b antibody, cyclin D2 S homeolog antibody, cyclin D2 antibody, G1/S-specific cyclin-D2 antibody, cyclin D2, a antibody, cyclin D2 L homeolog antibody, ccnd2b antibody, ccnd2.S antibody, CCND2 antibody, ccnd2 antibody, ccnd2a antibody, Ccnd2 antibody, ccnd2.L antibody
    背景
    Cyclin D2, also known as CCND2, is a human gene. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin D1, Cyclin D2 and Cyclin D3 are the members of the cyclin family. Cyclin D2 mapped to 12p131, since the CCND1 gene is on 11q13, this may be another bit of evidence of the homology of chromosomes 11 and 12. Choi D et al proved the expression of pseudogene cyclin D2 mRNA in the human ovary increases with age, which may be a novel marker for decreased ovarian function associated with the aging process.2 And knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. Inaba et al. (1992) used murine cDNA clones for 3 cyclin D genes that are normally expressed during the G1 phase of the cell cycle to clone the cognate human genes. D-type cyclins (cyclins D1, D2, and D3) are regarded as essential links between cell environment and the core cell cycle machinery. Cyclin D2(CCND2) gene ia assigned to 12p13.Synonyms: CCND2, Cyclin-D2
    基因ID
    894
    NCBI登录号
    NP_001750
    UniProt
    P30279
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases
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