×
我们推荐在您的浏览器上开启Javascript,以获得最佳效果。
CDKN1B 抗体
CDKN1B
适用: 人, 小鼠, 大鼠
WB, IF
宿主: 小鼠
Monoclonal
IMD-27
unconjugated
CDKN1B抗体详情
(hide)
抗原
See all CDKN1B 抗体
CDKN1B
(Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
适用
All reactivities for CDKN1B 抗体
人, 小鼠, 大鼠
宿主
All hosts for CDKN1B 抗体
小鼠
克隆类型
All clonalities for CDKN1B 抗体
单克隆
标记
All conjugates for CDKN1B 抗体
This CDKN1B antibody is un-conjugated
应用范围
All applications for CDKN1B 抗体
Western Blotting (WB), Immunofluorescence (IF)
特异性
This antibody reacts to CDKN1B.
纯化方法
Affinity chromatography
免疫原
recombinant rodent p27Kip1 protein
克隆位点
IMD-27
亚型
IgG1
Top Product
Discover our top product CDKN1B Primary Antibody
Alternatives
(show)
使用细节
(hide)
应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
(hide)
溶解方式
Restore with 1.2 % sodium acetate or neutral PBS
浓度
0,1 mg/mL
缓冲液
1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
-20 °C
储存方法
Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
CDKN1B目标详情
(hide)
抗原
CDKN1B
(Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
别名
CDKN1B / KIP1 (CDKN1B 产品 )
别名
CDKN4 antibody, KIP1 antibody, MEN1B antibody, MEN4 antibody, P27KIP1 antibody, cdkn1b antibody, sb:cb611 antibody, wu:fb63g10 antibody, wu:fb64g10 antibody, wu:fe18e03 antibody, CDKN1B antibody, Kip1 antibody, p27 antibody, FAM14D antibody, ISG12 antibody, ISG12A antibody, P27 antibody, Cdki1b antibody, AA408329 antibody, AI843786 antibody, p27Kip1 antibody, cdkn1bl antibody, cyclin dependent kinase inhibitor 1B antibody, cyclin-dependent kinase inhibitor 1Bb antibody, interferon alpha inducible protein 27 antibody, cyclin-dependent kinase inhibitor 1B antibody, cyclin-dependent kinase inhibitor 1Ba antibody, CDKN1B antibody, cdkn1bb antibody, IFI27 antibody, Cdkn1b antibody, cdkn1ba antibody
背景
P27(kip1), also known as cyclin dependent kinase inhibitor 1B(CDKN1B), is a major target of AFX-like forkhead proteins. CDKN1B (p27) belongs to the Cip/Kip family and functions as an important cell cycle gatekeeper.Phosphorylation leads to the ubiquitination and degradation of CDKN1B. P27(kip1) mapped to 12p13. An increase in p27 causes proliferating cells to exit from the cell cycle, and a decrease in p27 is necessary for quiescent cells to resume division. Abnormally low amounts of p27 are associated with pathological states of excessive cell proliferation, especially cancers. Overexpression of p27Kip1 lengthens the G1 phase in a mouse model that targets inducible gene expression to central nervous system progenitor cells.Synonyms: Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1
基因ID
1027
NCBI登录号
NP_004055
UniProt
P46527
途径
Cell Division Cycle , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Positive Regulation of Peptide Hormone Secretion , Negative Regulation of Hormone Secretion , Sensory Perception of Sound , Mitotic G1-G1/S Phases , DNA Replication , Positive Regulation of Endopeptidase Activity , Synthesis of DNA , Autophagy
Recently viewed
(hide)