anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) 抗体

The protein encoded by SMARCB1 is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. 再加上,我们可以发SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 蛋白 (20)SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 试剂盒 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
SMARCB1 6598 Q12824
SMARCB1 20587 Q9Z0H3
SMARCB1 361825  

antibodies-online.cn销售最多的anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 抗体

Showing 10 out of 134 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB SMARCB1 Antibody (N-term) (ABIN658274) western blot analysis in mouse brain tissue lysates (35 µg/lane). This demonstrates the SMARCB1 antibody detected the SMARCB1 protein (arrow). 400 μL Log in to see 5至8个工作日
¥2,325.14
详细
Cow 非结合性 IHC, WB WB Suggested Anti-SMARCB1  Antibody Titration: 0.2-1 µg/mL  Positive Control: Human Thymus 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
非结合性 WB WB Suggested Anti-SMARCB1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate WB Suggested Anti-SMARCB1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: Jurkat cell lysate  SMARCB1 is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
非结合性 IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL   Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;   Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 100 μL Log in to see 5至7个工作日
¥2,709.56
详细
小鼠 非结合性 WB SMARCB1 monoclonal antibody (M01), clone 3E10. Western Blot analysis of SMARCB1 expression in Hela NE. 0.1 mg Log in to see 11至15个工作日
¥3,179.71
详细
非结合性 ICC, IF, IHC, IHC (p), IP, WB Western Blot and Immunoprecipitation: SMARCB1/SNF5 Antibody [ABIN252863] - Detection of Human and Mouse SMARCB1/SNF5 by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded), 293T (T, 50 mcg) and mouse NIH3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti- SMARCB1/SNF5 antibody ABIN252863 used for WB at 0.4 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. SMARCB1/SNF5 was also immunoprecipitated by another rabbit anti-SMARCB1/SNF5 antibody, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 10 seconds (A) and 3 minutes (B). Western Blot: SNF5 Antibody [ABIN2528635] - Whole cell lysate (50 ug) from HeLa, 293T, and mouse NIH3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-SMARCB1/SNF5 antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Log in to see 25至31个工作日
¥3,977.17
详细
小鼠 非结合性 IF, WB Western blot analysis of BAF47 on a mouse cerebrum lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the anti- BAF47 antibody. 50 μg Log in to see 24至30个工作日
¥1,258.37
详细
Cow 非结合性 WB 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
非结合性 IHC (p), WB Anti-SNF5 antibody, Western blotting Lane 1: Rat Kidney Tissue Lysate Lane 2: Human Placenta Tissue Lysate Lane 3: Rat Spleen Tissue Lysate Lane 4: PC-12 Cell Lysate Lane 5: HELA Cell Lysate Lane 6: JURKAT Cell Lysate Lane 7: 293T Cell Lysate Lane 3: Recombinant Human SMARCB1 Protein 2.5ng 100 μg Log in to see 26至32个工作日
¥2,560.58
详细
非结合性 ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: SNF5 Antibody [NBP1-90014] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli. Western Blot: SNF5 Antibody [NBP1-90014] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Log in to see 28至35个工作日
¥3,591.24
详细

通过反应活性、应用领域、克隆类型和共轭标记 SMARCB1 抗体

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引用最多的anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 抗体

  1. Human Monoclonal SMARCB1 Primary Antibody for IF, WB - ABIN968741 : Bruder, Dumanski, Kedra: The mouse ortholog of the human SMARCB1 gene encodes two splice forms. in Biochemical and biophysical research communications 1999 (PubMed)
    Show all 3 references for 968741

  2. Human Polyclonal SMARCB1 Primary Antibody for WB - ABIN658274 : Bakshi, Hassan, Pratap, Lian, Montecino, van Wijnen, Stein, Imbalzano, Stein: The human SWI/SNF complex associates with RUNX1 to control transcription of hematopoietic target genes. in Journal of cellular physiology 2010 (PubMed)
    Show all 2 references for 658274

  3. Human Polyclonal SMARCB1 Primary Antibody for WB - ABIN2778302 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006 (PubMed)
    Show all 2 references for 2778302

  4. Human Polyclonal SMARCB1 Primary Antibody for ICC, IF - ABIN4354923 : Singh, Archer: Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation. in Nucleic acids research 2014 (PubMed)

  5. Human Polyclonal SMARCB1 Primary Antibody for ICC, IF - ABIN252863 : Young, Jacks: Tissue-specific p19Arf regulation dictates the response to oncogenic K-ras. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)

  6. Human Monoclonal SMARCB1 Primary Antibody for WB - ABIN393962 : Wu, Ho, Lin, Lin: Rhabdoid papillary meningioma: a clinicopathologic case series study. in Neuropathology : official journal of the Japanese Society of Neuropathology 2011 (PubMed)

  7. Human Polyclonal SMARCB1 Primary Antibody for IF (p), IHC (p) - ABIN762566 : McAndrew, Gjidoda, Tagore, Miksanek, Floer: Chromatin Remodeler Recruitment during Macrophage Differentiation Facilitates Transcription Factor Binding to Enhancers in Mature Cells. in The Journal of biological chemistry 2016 (PubMed)

  8. Cow (Bovine) Polyclonal SMARCB1 Primary Antibody for IHC, WB - ABIN2778301 : Mueller, Eum, Lass, Paulus, Sarkar, Bruck, von Deimling: No evidence of hSNF5/INI1 point mutations in choroid plexus papilloma. in Neuropathology and applied neurobiology 2004 (PubMed)

更多抗SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1的相互作用对抗体

Human SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) interaction partners

  1. Interactions have been indicated between SMARCB1/INI1 protein and key proteins in various pathways related to tumor proliferation and progression.

  2. The common loss of INI1 expression in rhabdoid and non-rhabdoid tumors will also open new therapeutic doors by developing targeted therapy strategies which may help to consolidate an initial treatment response to conventional radiochemotherapy.

  3. Biallelic alterations in the INI1 gene were identified in 4 of the 5 cases of atypical teratoid/rhabdoid tumors. Three of the 4 cases harbored 2 different mutations, presumably on different alleles (compound heterozygous mutations), and 1 case of which had a splice-site mutation.

  4. The epithelioid variant of schwannoma is rare, and loss of SMARCB1/INI1 expression has been observed in a subset of cases. Our aim was to further define the clinicopathologic features and to evaluate SMARCB1/INI1 deficiency in a large cohort of 65 epithelioid schwannomas diagnosed between 2002 and 2015

  5. SMARCB1 is required for the integrity of SWI (显示 SMARCA1 抗体)/SNF (显示 SNRPA 抗体) complexes.

  6. INI1 loss occurs rarely in colorectal carcinoma, where it is associated with higher grade, larger tumor size, poorer survival, mismatch repair deficiency, and BRAFV600E mutation.

  7. SWI (显示 SMARCA1 抗体)/SNF (显示 SNRPA 抗体) complexes lacking SMARCB1 are vital determinants of drug sensitivity, not just to TOP2A (显示 TOP2A 抗体)-targeted agents, but to the much broader range of cancer drugs effluxed by ABCB1 (显示 ABCB1 抗体).

  8. SMARCB1-deficient sinonasal carcinoma represents an emerging poorly differentiated/undifferentiated sinonasal carcinoma.

  9. Deletions in INI1 gene is associated with Small cell undifferentiated hepatoblastomas.

  10. Our results confirm the pathogenic involvement of SMARCB1/INI1 in childhood chordoma

Mouse (Murine) SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) interaction partners

  1. The occurrence of intracranial rhabdoid tumours depends on control of Smarcb1 inactivation.

  2. These results support recent findings regarding the effectivity of EGFR (显示 EGFR 抗体) inhibitors in hindering the proliferation of human MRT cells and demonstrate that activation of EGFR (显示 EGFR 抗体) signaling in Rhabdoid tumors is SMARCB1 dependent.

  3. these findings uncover a novel role for Snf5 in oligodendrocyte generation and survival, and they offer evidence of the first genetically engineered mouse model for AT/RT in the CNS.

  4. This study show here that loss of Smarcb1 and Smarca4 (显示 SMARCA4 抗体) leads to severe proliferation deficits of granule neuron precursors and a hypoplastic cerebellum.

  5. results show that Smarcb1 is required for transcriptional activation of Igfbp7 (显示 IGFBP7 抗体) and show that re-introduction of Igfbp7 (显示 IGFBP7 抗体) alone can hinder tumor development; results define a novel mechanism for Smarcb1-mediated tumorigenesis

  6. We find that inactivation of either Brg1 (显示 SMARCA4 抗体) or Smarcb1 leads to disruptions of specific nucleosome patterning combined with a loss of overall nucleosome occupancy at a large number of promoters, regardless of their association with CpG islands.

  7. SNF5 is a key mediator of Hedgehog (显示 SHH 抗体) signaling and that aberrant activation of GLI1 (显示 GLI1 抗体) is a previously undescribed targetable mechanism contributing to the growth of malignant rhabdoid tumor cells.

  8. Loss of the SNF5 tumor suppressor leads to elevated expression of the Polycomb (显示 CBX2 抗体) gene EZH2 (显示 EZH2 抗体).

  9. SNF5 knockdown inhibits p53 (显示 TP53 抗体) translation by eIF4E (显示 EIF4E 抗体) and replacement of eIF4E (显示 EIF4E 抗体) in SNF5 knockdown cells restores p53 (显示 TP53 抗体) expression and cell survival

  10. The loss of this protein, a core subunit of SWI (显示 SMARCA1 抗体)/SNF (显示 SNRPA 抗体), results in highly penetrant cancer predisposition with 100% of mice developing mature CD8 (显示 CD8A 抗体)(+)T cell lymphoma or rare rhabdoid tumors with a median onset of only 11 weeks.

SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) 抗原简介

蛋白简介

The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SMARCB1

  • matrix metallopeptidase 11 (stromelysin 3) (MMP11) 抗体
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 (SMARCB1) 抗体
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 (Smarcb1) 抗体
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 (smarcb1) 抗体
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b (smarcb1b) 抗体
  • AU020204 抗体
  • Baf47 抗体
  • fc51b01 抗体
  • hSNFS 抗体
  • Ini1 抗体
  • MRD15 抗体
  • RDT 抗体
  • RTPS1 抗体
  • Sfh1p 抗体
  • smarcb1 抗体
  • Snf5 抗体
  • SNF5/INI1 抗体
  • SNF5L1 抗体
  • Snr1 抗体
  • wu:fc51b01 抗体

Protein level used designations for SMARCB1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 , matrix metalloproteinase 11 (stromelysin 3) , BAF47 , BRG1-associated factor 47 , SNF5 homolog , hSNF5 , integrase interactor 1 protein , malignant rhabdoid tumor suppressor , sucrose nonfermenting, yeast, homolog-like 1 , mSNF5 , SWI/SNF-related matrix associated protein

GENE ID SPECIES
769489 Gallus gallus
537412 Bos taurus
6598 Homo sapiens
20587 Mus musculus
443934 Xenopus laevis
486407 Canis lupus familiaris
361825 Rattus norvegicus
30731 Danio rerio
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