anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) 抗体

The protein encoded by SMARCB1 is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. 再加上,我们可以发SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 蛋白 (9)SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 试剂盒 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
SMARCB1 6598 Q12824
SMARCB1 20587 Q9Z0H3
SMARCB1 361825  
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antibodies-online.cn销售最多的anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 抗体

Showing 10 out of 133 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB WB Suggested Anti-SMARCB1 <br /> Antibody Titration: 0.2-1 µg/mL <br /> Positive Control: Human Thymus 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 WB <b>WB Suggested Anti-SMARCB1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-SMARCB1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: Jurkat cell lysate <br /> SMARCB1 is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 WB SMARCB1 Antibody (N-term) (ABIN658274) western blot analysis in mouse brain tissue lysates (35 µg/lane). This demonstrates the SMARCB1 antibody detected the SMARCB1 protein (arrow). 400 μL Log in to see 10至11个工作日
$324.50
详细
非结合性 IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL   Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;   Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 100 μL Log in to see 3至7个工作日
$307.45
详细
小鼠 非结合性 IF, WB Western blot analysis of BAF47 on a mouse cerebrum lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the anti- BAF47 antibody. 50 μg Log in to see 6至8个工作日
$154.07
详细
非结合性 ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: SNF5 Antibody [NBP1-90014] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli. Western Blot: SNF5 Antibody [NBP1-90014] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Log in to see 10至13个工作日
$439.69
详细
小鼠 非结合性 WB SMARCB1 monoclonal antibody (M01), clone 3E10. Western Blot analysis of SMARCB1 expression in Hela NE. 0.1 mg Log in to see 8至11个工作日
$450.00
详细
非结合性 ICC, IF, IHC, IHC (p), IP, WB Western Blot and Immunoprecipitation: SMARCB1/SNF5 Antibody [ABIN252863] - Detection of Human and Mouse SMARCB1/SNF5 by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded), 293T (T, 50 mcg) and mouse NIH3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti- SMARCB1/SNF5 antibody ABIN252863 used for WB at 0.4 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. SMARCB1/SNF5 was also immunoprecipitated by another rabbit anti-SMARCB1/SNF5 antibody, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 10 seconds (A) and 3 minutes (B). Western Blot: SNF5 Antibody [ABIN2528635] - Whole cell lysate (50 ug) from HeLa, 293T, and mouse NIH3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-SMARCB1/SNF5 antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Log in to see 7至9个工作日
$486.94
详细
非结合性 ChIP, IC, IF, IHC, IP, WB Immunofluorescent analysis of INI1 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody i 200 μL Log in to see 13至14个工作日
$487.50
详细

通过反应活性、应用领域、克隆类型和共轭标记 SMARCB1 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 抗体

  1. Human Monoclonal SMARCB1 Primary Antibody for IF, WB - ABIN968742 : Bruder, Dumanski, Kedra: The mouse ortholog of the human SMARCB1 gene encodes two splice forms. in Biochemical and biophysical research communications 1999 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal SMARCB1 Primary Antibody for IF, WB - ABIN968741 : Guidi, Sands, Zambrowicz, Turner, Demers, Webster, Smith, Imbalzano, Jones: Disruption of Ini1 leads to peri-implantation lethality and tumorigenesis in mice. in Molecular and cellular biology 2001 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal SMARCB1 Primary Antibody for WB - ABIN393962 : Wu, Ho, Lin, Lin: Rhabdoid papillary meningioma: a clinicopathologic case series study. in Neuropathology : official journal of the Japanese Society of Neuropathology 2011 (PubMed)

  4. Human Polyclonal SMARCB1 Primary Antibody for ICC, IF - ABIN252863 : Young, Jacks: Tissue-specific p19Arf regulation dictates the response to oncogenic K-ras. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)

  5. Human Monoclonal SMARCB1 Primary Antibody for IHC (p), ELISA - ABIN562912 : Scurr, Pupo, Becker, Lai, Schrama, Haferkamp, Irvine, Scolyer, Mann, Becker, Kefford, Rizos: IGFBP7 is not required for B-RAF-induced melanocyte senescence. in Cell 2010 (PubMed)

  6. Human Polyclonal SMARCB1 Primary Antibody for IF (p), IHC (p) - ABIN762566 : McAndrew, Gjidoda, Tagore, Miksanek, Floer: Chromatin Remodeler Recruitment during Macrophage Differentiation Facilitates Transcription Factor Binding to Enhancers in Mature Cells. in The Journal of biological chemistry 2016 (PubMed)

  7. Human Polyclonal SMARCB1 Primary Antibody for ICC, IF - ABIN4354923 : Singh, Archer: Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation. in Nucleic acids research 2014 (PubMed)

  8. Human Polyclonal SMARCB1 Primary Antibody for WB - ABIN2778302 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006 (PubMed)
    Show all 2 Pubmed References

更多抗SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1的相互作用对抗体

Human SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) interaction partners

  1. These highly mobile and invasive cells no longer depend on KRAS signaling and rely on the aberrant activation of mesenchymal programs regulated by the chromatin remodeling factor (显示 ASH1L 抗体) SMARCB1. Mouse models showed that Smarcb1 ablation could intensify cancer spread; conversely, restoring Smarcb1 slowed tumor growth and restored the cells to their less invasive, epithelial form

  2. BAF57 (显示 SMARCE1 抗体), BAF60a (显示 SMARCD1 抗体) and SNF5 might act as novel pro-senescence factors in both normal and tumor human skin cells

  3. Low SNF5 expression is associated with Hepatocellular Carcinoma.

  4. SMARCB1 is required for widespread BAF (显示 BANF1 抗体) complex-mediated activation of enhancers and bivalent promoters.

  5. Interactions have been indicated between SMARCB1/INI1 protein and key proteins in various pathways related to tumor proliferation and progression.

  6. The common loss of INI1 expression in rhabdoid and non-rhabdoid tumors will also open new therapeutic doors by developing targeted therapy strategies which may help to consolidate an initial treatment response to conventional radiochemotherapy.

  7. Biallelic alterations in the INI1 gene were identified in 4 of the 5 cases of atypical teratoid/rhabdoid tumors. Three of the 4 cases harbored 2 different mutations, presumably on different alleles (compound heterozygous mutations), and 1 case of which had a splice-site mutation.

  8. The epithelioid variant of schwannoma is rare, and loss of SMARCB1/INI1 expression has been observed in a subset of cases. Our aim was to further define the clinicopathologic features and to evaluate SMARCB1/INI1 deficiency in a large cohort of 65 epithelioid schwannomas diagnosed between 2002 and 2015

  9. SMARCB1 is required for the integrity of SWI (显示 SMARCA1 抗体)/SNF (显示 SNRPA 抗体) complexes.

  10. INI1 loss occurs rarely in colorectal carcinoma, where it is associated with higher grade, larger tumor size, poorer survival, mismatch repair deficiency, and BRAFV600E mutation.

Mouse (Murine) SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) interaction partners

  1. Data show that early Smarcb1 loss causes rhabdoid tumors whereas loss at later stages combined with Nf2 (显示 NF2 抗体) gene inactivation causes shwannomas.

  2. The occurrence of intracranial rhabdoid tumours depends on control of Smarcb1 inactivation.

  3. These results support recent findings regarding the effectivity of EGFR (显示 EGFR 抗体) inhibitors in hindering the proliferation of human MRT cells and demonstrate that activation of EGFR (显示 EGFR 抗体) signaling in Rhabdoid tumors is SMARCB1 dependent.

  4. these findings uncover a novel role for Snf5 in oligodendrocyte generation and survival, and they offer evidence of the first genetically engineered mouse model for AT/RT in the CNS.

  5. This study show here that loss of Smarcb1 and Smarca4 (显示 SMARCA4 抗体) leads to severe proliferation deficits of granule neuron precursors and a hypoplastic cerebellum.

  6. results show that Smarcb1 is required for transcriptional activation of Igfbp7 (显示 IGFBP7 抗体) and show that re-introduction of Igfbp7 (显示 IGFBP7 抗体) alone can hinder tumor development; results define a novel mechanism for Smarcb1-mediated tumorigenesis

  7. We find that inactivation of either Brg1 (显示 SMARCA4 抗体) or Smarcb1 leads to disruptions of specific nucleosome patterning combined with a loss of overall nucleosome occupancy at a large number of promoters, regardless of their association with CpG islands.

  8. SNF5 is a key mediator of Hedgehog (显示 SHH 抗体) signaling and that aberrant activation of GLI1 (显示 GLI1 抗体) is a previously undescribed targetable mechanism contributing to the growth of malignant rhabdoid tumor cells.

  9. Loss of the SNF5 tumor suppressor leads to elevated expression of the Polycomb (显示 CBX2 抗体) gene EZH2 (显示 EZH2 抗体).

  10. SNF5 knockdown inhibits p53 (显示 TP53 抗体) translation by eIF4E (显示 EIF4E 抗体) and replacement of eIF4E (显示 EIF4E 抗体) in SNF5 knockdown cells restores p53 (显示 TP53 抗体) expression and cell survival

SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) 抗原简介

蛋白简介

The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SMARCB1

  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 (SMARCB1) 抗体
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 (Smarcb1) 抗体
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 S homeolog (smarcb1.S) 抗体
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b (smarcb1b) 抗体
  • AU020204 抗体
  • Baf47 抗体
  • fc51b01 抗体
  • hSNFS 抗体
  • Ini1 抗体
  • MRD15 抗体
  • RDT 抗体
  • RTPS1 抗体
  • Sfh1p 抗体
  • smarcb1 抗体
  • Snf5 抗体
  • SNF5/INI1 抗体
  • SNF5L1 抗体
  • Snr1 抗体
  • wu:fc51b01 抗体

Protein level used designations for SMARCB1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 , matrix metalloproteinase 11 (stromelysin 3) , BAF47 , BRG1-associated factor 47 , SNF5 homolog , hSNF5 , integrase interactor 1 protein , malignant rhabdoid tumor suppressor , sucrose nonfermenting, yeast, homolog-like 1 , mSNF5 , SWI/SNF-related matrix associated protein

GENE ID SPECIES
769489 Gallus gallus
537412 Bos taurus
6598 Homo sapiens
20587 Mus musculus
443934 Xenopus laevis
486407 Canis lupus familiaris
361825 Rattus norvegicus
30731 Danio rerio
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