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This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1\\/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. 再加上，我们可以发Paternally Expressed 10 抗体 (109) 和 Paternally Expressed 10 蛋白 (4)和数多这个蛋白质的别的产品。
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miR (显示 MLXIP ELISA试剂盒)-122 suppresses PEG10 expression via direct binding to the 3'-UTR (显示 UTS2R ELISA试剂盒) of the PEG10 transcript.
PEG10 expression associates with the lymph node metastasis and overall survival of hepatocellular carcinoma patients.PEG10 expression level is essential for TGF-beta1 (显示 TGFB1 ELISA试剂盒) induced epithelialmesenchymal transition.
Knockdown of PEG10 expression by siRNA could lead to growth arrest and cell apoptosis in diffuse large B cell lymphoma cells in vitro.
PEG10 protein could be a potential biomarker predicting early recurrence and recurrence-free survival in HCC (显示 FAM126A ELISA试剂盒) patients after curative resection, even in those with normal serum alpha-fetoprotein (显示 AFP ELISA试剂盒) levels.
Study shows that expression level of PEG10 was significantly elevated in breast cancer tissues and associated with distant metastasis and poor clinical outcome and provides evidence that PEG10 is a crucial oncogene (显示 RAB1A ELISA试剂盒).
important role in trophoblast proliferation and promotes trophoblast invasion through TIMP-1 (显示 TIMP1 ELISA试剂盒)
Results revealed that PEG10 high expression was closely associated with the TNM (显示 ODZ1 ELISA试剂盒) classification in lung cancer and is a critical indicator for poor prognosis. Also, It promotes significantly proliferation, migration and invasion of A549 lung cancer cells.
The downregulated expression of the imprinted gene PEG10 may be an important reason for the occurrence of preeclampsia.
elevated expression of PEG10 is likely to be involved in the pathophysiology of preeclampsia
promotes migration of Burkitt's lymphoma cells via upregulation of matrix metalloproteinase-2 (显示 MMP2 ELISA试剂盒) and -9
polymorphisms in PEG10 and PPP1R9A (显示 PPP1R9A ELISA试剂盒) were associated with fat deposition and carcass traits
The imprinting status of PEG10 is conserved in swine as paternal expression was demonstrated by quantitative allelic sequencing of reciprocal crosses in fetal tissues of whole brain, carcass, liver and placentae.
The expression patterns of PLAGL1 (显示 PLAGL1 ELISA试剂盒) and PEG10 genes in two breeds of swine are reported.
the abnormal DNA methylation (显示 HELLS ELISA试剂盒) epigenetic reprogramming of imprinting PEG10 gene in placenta may be one of the main causes of the abnormal development and death of the transgenic cloned cattle.
Loss of DNA methylation (显示 HELLS ELISA试剂盒) at the Peg10 imprinted gDMD associated with decreased embryonic viability and decreased labyrinthine volume.
Knockdown of Syncytin-A demonstrated a functional regulation of cell-cell fusion, where knockdown of Peg10 showed no involvement in cell fusion
Programmed -1 ribosomal frameshifting in mouse and human Peg10 genes.
Peg10 gene is imprinted, with preferential expression from the paternal allele, and its deletion results in early embryonic lethality.
Results indicate that the induction of the imprinted gene paternally expressed 10 (PEG10) may play an important role during liver regeneration or carcinogenesis of the hepatocyte.
These findings strongly indicate that peg10 plays a crucial role at the immediate early (显示 JUN ELISA试剂盒) stage of adipocyte differentiation.
the ORF1 (显示 MED14 ELISA试剂盒)-2 protein of PEG10, synthesized utilizing the most efficient -1 frameshift mechanism yet documented in vivo, will have an essential function that is intrinsic to the importance of PEG10 in mammals
This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.
paternally expressed 10
, MEF3 like 1
, MEF3-like protein 1
, embryonal carcinoma differentiation regulated
, embryonal carcinoma differentiation-regulated protein
, mammalian retrotransposon-derived protein 2
, myelin expression factor 3-like protein 1
, paternally expressed gene 10 protein
, retrotransposon gag domain containing 3
, retrotransposon gag domain-containing protein 3
, retrotransposon-derived gag-like polyprotein
, retrotransposon-derived protein PEG10
, ty3/Gypsy-like protein
, MyEF-3 like
, embryonal carcinoma differentiation regulated protein
, myelin expression factor 3