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PDLIM5 encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. 再加上，我们可以发PDZ and LIM Domain 5 蛋白 (4) 和 PDZ and LIM Domain 5 试剂盒 (1)和数多这个蛋白质的别的产品。
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Human Polyclonal PDLIM5 Primary Antibody for ICC, IF - ABIN4344624
Li, Ponten, dos Remedios: The interactome of LIM domain proteins: the contributions of LIM domain proteins to heart failure and heart development. in Proteomics 2012
Human Polyclonal PDLIM5 Primary Antibody for ELISA, WB - ABIN564628
Cheng, Kimura, Peter, Cui, Ouyang, Shen, Liu, Gu, Dalton, Evans, Knowlton, Peterson, Chen: Loss of enigma homolog protein results in dilated cardiomyopathy. in Circulation research 2010
findings show the temporal & spatial expression patterns of the 3 Enigma (显示 PDLIM7 抗体) family members & their PDZ (显示 INADL 抗体) & LIM domain encoding splice forms during embryogenesis
PDLIM5 was strongly up-regulated during cardiomyogenesis and novel stage-specific isoforms were detected for PDLIM5
Findings provide evidence of shared genetic variants in PDLIM5 gene influencing alcohol dependence, type 2 diabetes, and hypertension.
The study provides evidence of several genetic variants within the PDLIM5 gene and interactions between PDLIM5 and steroid use influencing cancer.
It can be deduced that the nonsynonymous rs7690296 polymorphism of PDLIM5 could play an important role in the pathophysiology of both bipolar disorder and schizophrenia.
PDLIM5 (rs17021918,T), SLC22A3 (显示 OCT3 抗体) (rs9364554,C) and NKX3-1 (显示 NKX3-1 抗体) (rs1512268,A) SNPs might not be associated with prostate cancer in Chinese men.
The significant difference in expression of PDLIM5 mRNA in the peripheral blood leukocytes of treatment-naive bipolar (BPD (显示 MOD(MDG4) 抗体)) patients versus that of healthy control subjects suggests that it may be a good biological marker for BPD (显示 MOD(MDG4) 抗体).
LIM domains have a novel molecular function: the regulation of PKC activities in a PKC isoform-specific manner.
Altered expression of LIM was found in brains and lymphoblastoid cells from patients with bipolar disorder.
It is confirmed a decreased expression of LIM in the lymphoblastoid cell lines from patients with bipolar I disorder and schizophrenia.
Western blot studies of muscle tissues revealed that ENH4 is present only in skeletal muscle and there is a specific distribution of ENH members between skeletal and cardiac muscles, which is different in human and mouse.
Collectively, our results suggest that ENH1 plays an important role in the activation of myogenesis through the repression of Id2 activity.
Cypher (显示 LDB3 抗体) and ENH redundantly play an essential role in sustaining Z-line structure from the earliest stages of cardiac function, and are redundantly required to maintain normal embryonic heart function and embryonic viability.
PDLIM5 is involved in psychiatric disorders, including mood disorders
ENH1 with multiple protein-protein interaction modules is essential for differentiation of striated (显示 NSDHL 抗体) muscles, whereas ectopic expression of LIM domain-less ENH disrupts normal muscle differentiation.
coordinated and stepwise splicing transitions result in the production of specific ENH transcripts in mature striated (显示 NSDHL 抗体) muscles.
Deletion of ENH leads to destabilization of this protein complex and dilated cardiomyopathy in mice.
Antagonistic splice variants of enigma (显示 PDLIM7 抗体) may play a central role in the adaptive changes of the link between mechanical stress-sensing and signalling occurring during embryonic development and/or heart hypertrophy.
These results identify Enigma as a novel APS-binding protein and suggest that the APS/Enigma complex plays a critical role in actin cytoskeleton organisation.
ENH is a restraining factor of the oncogenic activity of inhibitor of DNA binding 2 proteins in neural tumors
This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants.
PDZ and LIM domain protein 5
, enigma homolog
, enigma-like LIM domain protein
, enigma-like PDZ and LIM domains protein
, PDZ and LIM domain 5
, PDZ and LIM domain protein 5-like