Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1) ELISA试剂盒

Histone methyltransferase that plays an essential role in early development and hematopoiesis. 再加上,我们可以发Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 抗体 (10)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
MLL1 315606  
MLL1 214162 P55200
MLL1    

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适于 Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1) interaction partners

  1. These results reveal a cooperative transcriptional activation mechanism of AEP (显示 LGMN ELISA试剂盒) and DOT1L (显示 DOT1L ELISA试剂盒) and suggest a molecular rationale for the simultaneous inhibition of the MLL (显示 MLL ELISA试剂盒) fusion-AF4 complex and DOT1L (显示 DOT1L ELISA试剂盒) for more effective treatment of MLL (显示 MLL ELISA试剂盒)-rearranged leukemia.

  2. This study demonstrated that Kmt2a (显示 MLL ELISA试剂盒) regulates synaptic plasticity in striatal neurons and provides an epigenetic drug target for anxiety and dopamine-mediated behaviors.

  3. Inactivation of Kmt2a in Men1-deficient mice accelerated pancreatic islet tumorigenesis and shortened the average life span. Increases in cell proliferation were observed in mouse pancreatic islet tumors upon inactivation of both Kmt2a and Men1.

  4. Data suggest that RAS-homolog enriched in brain protein (Rheb1) promotes MLL-AF9 fusion protein initiated acute myeloid leukemia (AML) progression through target of rapamycin complex 1 (mTORC1) signaling pathway.

  5. HoxBlinc RNA Recruits Set1 (显示 SETD1A ELISA试剂盒)/MLL (显示 MLL ELISA试剂盒) Complexes to Activate Hox (显示 MSH2 ELISA试剂盒) Gene Expression Patterns and Mesoderm Lineage Development.

  6. MLL1 and DOT1L (显示 DOT1L ELISA试剂盒) cooperate with meningioma-1 to induce acute myeloid leukemia (显示 BCL11A ELISA试剂盒).

  7. Set1 role in cellular reprogramming and its interactions with Dpy30,Myc,Sox2 and Ash2l reprogramming factors

  8. The present study examined the mechanism underlying the development of KMT2A (MLL (显示 MLL ELISA试剂盒))-rearranged infant leukemia in response to in utero exposure to etoposide in a mouse model.

  9. We have demonstrated that the Mll1 gene is critical to Th1 (显示 HAND1 ELISA试剂盒) differentiation in humans and mice

  10. MLL is the key Taspase1 substrate whose cleavage is required for MMTV-neuinduced tumor formation.

Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1) 抗原简介

Antigen Summary

Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the MLL1/MLL complex, it specifically mediates H3K4me, a specific tag for epigenetic transcriptional activation. Has weak methyltransferase activity by itself, and requires other component of the MLL1/MLL complex to obtain full methyltransferase activity. Has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', while it has higher activity toward H3 acetylated on 'Lys-9'. Required for transcriptional activation of HOXA9. Promotes PPP1R15A-induced apoptosis (By similarity).

Gene names and symbols associated with MLL1

  • lysine (K)-specific methyltransferase 2A (Kmt2a) 抗体
  • 6430520K01 抗体
  • ALL-1 抗体
  • All1 抗体
  • Cxxc7 抗体
  • HRX 抗体
  • HTRX1 抗体
  • mKIAA4050 抗体
  • Mll 抗体
  • Mll1 抗体

Protein level used designations for MLL1

Mixed-lineage leukemia (also acute lymphocytic leukemia 1 or tritorax Drosophila gene) , histone-lysine N-methyltransferase MLL , myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) , myeloid/lymphoid or mixed-lineage leukemia 1 , histone-lysine N-methyltransferase 2A , lysine N-methyltransferase 2A , myeloid/lymphoid or mixed-lineage leukemia protein 1 , trithorax Drosophila , zinc finger protein HRX

GENE ID SPECIES
315606 Rattus norvegicus
214162 Mus musculus
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