anti-MAP/microtubule Affinity-Regulating Kinase 2 (MARK2) 抗体

MARK2 encodes a member of the Par-1 family of serine/threonine protein kinases. 再加上,我们可以发MAP/microtubule Affinity-Regulating Kinase 2 蛋白 (10)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MARK2 2011 Q7KZI7
MARK2 13728 Q05512
MARK2 60328 O08679
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antibodies-online.cn销售最多的anti-MAP/microtubule Affinity-Regulating Kinase 2 抗体

Showing 10 out of 97 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IF, ELISA, WB Western blot analysis of extracts from COS7 cells, using MARK2 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using MARK2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 IHC (p), WB Western blot analysis of anti-EMK Antibody (C-term)(ABIN392538) in mouse thymus tissue lysates (35 µg/lane). EMK(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10至11个工作日
$324.50
详细
非结合性 EIA, IHC (p), WB 0.4 mL Log in to see 6至8个工作日
$390.50
详细
Cow 非结合性 EIA, WB 0.1 mg Log in to see 6至8个工作日
$419.10
详细
山羊 非结合性 ELISA, WB ABIN334431 (0.3µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6至7个工作日
$326.89
详细
非结合性 IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using MARK2 (Ab-596) Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HuvEc cells, using MARK2 (Ab-596) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
小鼠 非结合性 ELISA, WB Detection limit for recombinant GST tagged MARK2 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8至11个工作日
$450.00
详细
山羊 非结合性 ELISA, WB Western Blot: MARK2 Antibody [NBP1-00214] - (0.3ug/ml) staining of Human Brain (Cerebellum) 35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7至9个工作日
$408.19
详细
Cow 山羊 非结合性 ELISA, WB 100 μg Log in to see 7至9个工作日
$610.50
详细
非结合性 ELISA, IF, WB 100 μL Log in to see 16 Days
$175.80
详细

通过反应活性、应用领域、克隆类型和共轭标记 MARK2 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-MAP/microtubule Affinity-Regulating Kinase 2 抗体

  1. Human Polyclonal MARK2 Primary Antibody for IP, WB - ABIN4332738 : Kruse, Krantz, Barker, Coletta, Rafikov, Luo, Højlund, Mandarino, Langlais: Characterization of the CLASP2 Protein Interaction Network Identifies SOGA1 as a Microtubule-Associated Protein. in Molecular & cellular proteomics : MCP 2017 (PubMed)

  2. Human Polyclonal MARK2 Primary Antibody for ELISA, WB - ABIN314316 : Depasquale, Thompson: Prognosis in human melanoma: PAR-1 expression is superior to other coagulation components and VEGF. in Histopathology 2008 (PubMed)

  3. Human Polyclonal MARK2 Primary Antibody for IHC (p), WB - ABIN392538 : Blume-Jensen, Hunter: Oncogenic kinase signalling. in Nature 2001 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal MARK2 Primary Antibody for ELISA, WB - ABIN560734 : Hezel, Gurumurthy, Granot, Swisa, Chu, Bailey, Dor, Bardeesy, Depinho: Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. in Molecular and cellular biology 2008 (PubMed)

更多抗MAP/microtubule Affinity-Regulating Kinase 2的相互作用对抗体

Human MAP/microtubule Affinity-Regulating Kinase 2 (MARK2) interaction partners

  1. In the modeled structure of inactive MARK2, activation segment occludes the enzyme active site and assumes a relatively stable position.

  2. In conclusion, baicalin and DDP (显示 TIMM8A 抗体) were synergistic at inhibiting proliferation and invasion of human lung cancer cells at appropriate dosages and incubation time in the presence or absence of DDP (显示 TIMM8A 抗体) resistance. The attenuation of DDP (显示 TIMM8A 抗体) resistance was associated with downregulation of MARK2 and p-Akt (显示 AKT1 抗体).

  3. MARK2 plays a role in promoting malignant phenotypes of lung cancer.

  4. Phosphorylation of RNF41 (显示 RNF41 抗体) by Par-1b regulates basolateral membrane targeting of laminin-111 receptors.

  5. induces asymmetric inheritance of plasma membrane domains via LGN (显示 GPSM2 抗体)-dependent mitotic spindle orientation in proliferating hepatocytes

  6. Perturbation of PAR1b and SHP2 (显示 PTPN11 抗体) by CagA (显示 S100A8 抗体) underlies the oncogenic potential of CagA (显示 S100A8 抗体).

  7. The MARK2 binds to the N-terminal tail of Tau and selectively phosphorylates three major and five minor serine residues in the repeat domain and C-terminal tail.

  8. Hepatocyte Par1b defines lumen position in concert with the position of the astral microtubule anchoring complex LGN (显示 GPSM2 抗体)-NuMA (显示 NUMA1 抗体) to yield the distinct epithelial division phenotypes.

  9. automated image analysis of MT assembly dynamics identified MARK2 as a target regulated downstream of Rac1 that promotes oriented MT growth in the leading edge to mediate directed cell migration.

  10. The scaffolding adaptor GAB1 (显示 GAB1 抗体) interacts with two polarity proteins, PAR1 and PAR3 (显示 F2RL2 抗体).

Mouse (Murine) MAP/microtubule Affinity-Regulating Kinase 2 (MARK2) interaction partners

  1. These results indicate that the basal localization of Par-1b in the outer epithelial cells is required for myoepithelial cell compression, and Par-1b is required for myoepithelial differentiation, regardless of its localization.

  2. data suggest ectopic PAR1 (显示 F2R 抗体) expression is not tolerated in mouse platelets and indicate a different approach is required to develop a small animal model for the purpose of any future preclinical testing of PAR (显示 AFG3L2 抗体) antagonists as anti-platelet drugs

  3. a model whereby MARK2 negatively regulates insulin (显示 INS 抗体) sensitivity in peripheral tissue through inhibition of KSR1 (显示 KSR1 抗体)

  4. ROCK1 (显示 ROCK1 抗体)/PAR-1b-dependent regulation of basement membrane placement is required for the coordination of tissue polarity and the elaboration of tissue structure in the developing submandibular salivary gland.

  5. PAR1b plays a novel role in the maintenance of mature dendritic spine morphology by regulating microtubule growth and the accumulation of p140Cap (显示 SRCIN1 抗体) in dendritic spines.

  6. Par-1b is a regulator of glucose metabolism and adiposity in the whole animal

  7. Interaction of MARK2 with CaMKI (显示 CAMK1 抗体) results in a novel, calcium-dependent pathway that plays an important role in neuronal differentiation.

  8. Akt (显示 AKT1 抗体) enhances the activity of PAR1 (显示 F2R 抗体) to promote tau hyperphosphorylation at S262/S356, a tau species that is not recognized by the CHIP/Hsp90 (显示 HSP90 抗体) complex

  9. Coreduction of MARK2 and DCX (显示 DCX 抗体) resulted in a partial restoration of the normal neuronal migration phenotype in vivo. The kinetic behavior of the centrosomes reflected the different molecular mechanisms activated when either protein was reduced.

MAP/microtubule Affinity-Regulating Kinase 2 (MARK2) 抗原简介

蛋白简介

This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MARK2

  • microtubule affinity regulating kinase 2 (MARK2) 抗体
  • MAP/microtubule affinity regulating kinase 2 (Mark2) 抗体
  • microtubule affinity regulating kinase 2 (Mark2) 抗体
  • AU024026 抗体
  • Emk 抗体
  • EMK-1 抗体
  • EMK1 抗体
  • mKIAA4207 抗体
  • Par-1 抗体
  • Par-1b 抗体
  • Par1b 抗体

Protein level used designations for MARK2

ELKL motif kinase 1 , PAR1 homolog b , Ser/Thr protein kinase PAR-1B , serine/threonine protein kinase EMK , serine/threonine-protein kinase MARK2 , EMK-1 , EMK1 , serine/threonine kinase

GENE ID SPECIES
100049882 Equus caballus
2011 Homo sapiens
13728 Mus musculus
483769 Canis lupus familiaris
535197 Bos taurus
60328 Rattus norvegicus
100737238 Sus scrofa
100731733 Cavia porcellus
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