anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) 抗体

HSD17B10 encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. 再加上,我们可以发HSD17B10 试剂盒 (17)HSD17B10 蛋白 (16)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
HSD17B10 3028 Q99714
HSD17B10 15108  
HSD17B10 63864 O70351
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Showing 10 out of 126 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IHC (p), WB Western blot analysis of anti-ABAD Pab (ABIN390286) in mouse kidney tissue lysate.ABAD(arrow) was detected using the purified polyclonal antibody. Immunohistochemistry on Formalin-fixed and paraffin-embedded human prostate tissue. (Top)Coloration with the Anti-ABAD antibody at a 1:20 concentration. (Bottom)Antibody adsorbed to the antigen (peptide), negative control.Disappearance of cytoplasmic staining indicating the antibody is specific. Data and protocol courtesy of Marie-Hélène Levesque, Centre de Recherche du CHUL, Canada. 400 μL Log in to see 10至11个工作日
$324.50
详细
非结合性 EIA, IHC (p), WB Immunohistochemistry on Formalin-fixed and paraffin-embedded human prostate tissue. (Top)Coloration with the Anti-ABAD antibody at a 1:20 concentration. (Bottom)Antibody adsorbed to the antigen (peptide), negative control.Disappearance of cytoplasmic staining indicating the antibody is specific. Western blot analysis of anti-ABAD Pab in mouse kidney tissue lysate.ABAD(arrow) was detected using the purified Pab. 0.4 mL Log in to see 6至8个工作日
$390.50
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非结合性 WB 100 μg Log in to see 2至3个工作日
$245.00
详细
非结合性 IHC (p), WB Anti- ERAB Picoband antibody,IHC(P) IHC(P): Human Mammary Cancer Tissue 100 μg Log in to see 4至6个工作日
$240.00
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山羊 非结合性 ELISA, WB ABIN185330 staining (0.3µg/ml) of Human Brain lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 6至7个工作日
$326.89
详细
非结合性 IHC, ELISA, WB Western blot analysis of extracts from LOVO cells, using ERAB Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ERAB Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
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非结合性 ICC, IF, IHC (p), WB IHC-P Image ERAB antibody detects ERAB protein at mitochondria on mouse intestine by immunohistochemical analysis. Sample: Paraffin-embedded mouse intestine. ERAB antibody , dilution: 1:500. WB Image Sample (30 ug of whole cell lysate)    A: PC-12   12% SDS PAGE    antibody diluted at 1:5000   100 μL Log in to see 1至2个工作日
$358.60
详细
非结合性 ELISA, IHC, WB 100 μL Log in to see 16 Days
$175.80
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非结合性 WB   100 μL Log in to see 2至3个工作日
$306.90
详细
山羊 非结合性 ELISA, WB Western Blot: ERAB Antibody [ABIN268653] - Analysis of ERAB / HADH2 in Human Brain lysate (RIPA buffer, 30ug total protein per lane) using this antibody at 0.3ug/ml. Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 0.1 mg Log in to see 7至9个工作日
$408.19
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通过反应活性、应用领域、克隆类型和共轭标记 HSD17B10 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-HSD17B10 抗体

  1. Human Polyclonal HSD17B10 Primary Antibody for ELISA, WB - ABIN268653 : Tilton, Haidacher, Lejeune, Zhang, Zhao, Kurosky, Brasier, Denner: Diabetes-induced changes in the renal cortical proteome assessed with two-dimensional gel electrophoresis and mass spectrometry. in Proteomics 2007 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal HSD17B10 Primary Antibody for ELISA, WB - ABIN185330 : He, Schulz, Yang: A human brain L-3-hydroxyacyl-coenzyme A dehydrogenase is identical to an amyloid beta-peptide-binding protein involved in Alzheimer's disease. in The Journal of biological chemistry 1998 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal HSD17B10 Primary Antibody for IF, WB - ABIN516335 : Kristofiková, Bocková, Hegnerová, Bartos, Klaschka, Rícný, Rípová, Homola: Enhanced levels of mitochondrial enzyme 17beta-hydroxysteroid dehydrogenase type 10 in patients with Alzheimer disease and multiple sclerosis. in Molecular bioSystems 2009 (PubMed)

更多抗HSD17B10的相互作用对抗体

Human Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) interaction partners

  1. The S-nitrosation of a cysteine residue distal to the 3-hydroxyacyl-CoA dehydrogenase type 2 (HADH2) active site impaired catalytic activity.

  2. A computational study and enzyme inhibition assay with full length human 17-beta-HSD10 identifies risperidone as enzyme inhibitor and possible antineoplastic agent.

  3. Data suggest that HSD10 plays a role in alterations of energy metabolism by regulating mtDNA content in colorectal carcinomas.

  4. upon exposure to E2, ERalpha (显示 ESR1 抗体) rapidly localizes to mitochondria, in which it interacts with HSD17B10 to modulate the expression of mitochondrial RNA transcripts.

  5. Our findings demonstrate that overexpression of HSD10 accelerates pheochromocytoma cell growth, enhances cell respiration, and increases cellular resistance to cell death induction.

  6. Three HSD10 variants associated with neurodegenerative disorders are inactive with cardiolipin

  7. The authors demonstrate elevated amounts of unprocessed pre-tRNAs and mRNA transcripts encoding mitochondrial subunits indicating deficient RNase P activity in HSD10 disease.

  8. The study showed that pathogenic mutations impair SDR5C1-dependent dehydrogenation, tRNA processing and methylation.

  9. loss of HSD10 causes impaired mitochondrial precursor transcript processing which may explain mitochondrial dysfunction observed in HSD10 disease

  10. Defects in this gene are a cause of 17beta-hydroxysteroid dehydrogenase (显示 HSD17B7 抗体) type 10 (HSD10) deficiency. The encoded protein does not exhibit generalized alcohol dehydrogenase (显示 AKR1A1 抗体) activity as was previously thought.

Mouse (Murine) Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) interaction partners

  1. that 17beta-HSD-10 is a major product of both fetal and adult-type Leydig cells.

  2. ABAD enhances Abeta (显示 APP 抗体)-induced cell stress via mitochondrial dysfunction.Amyloid-beta peptide (Abeta (显示 APP 抗体)) binding alcohol dehydrogenase (显示 AKR1A1 抗体) (ABAD), an enzyme present in neuronal mitochondria, is a cofactor facilitating Abeta (显示 APP 抗体)-induced cell stress.

HSD17B10 抗原简介

蛋白简介

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Gene names and symbols associated with HSD17B10

  • hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10) 抗体
  • hydroxysteroid (17-beta) dehydrogenase 10 (hsd17b10) 抗体
  • hydroxysteroid 17-beta dehydrogenase 10 (HSD17B10) 抗体
  • hydroxysteroid (17-beta) dehydrogenase 10 L homeolog (hsd17b10.L) 抗体
  • hydroxysteroid (17-beta) dehydrogenase 10 (Hsd17b10) 抗体
  • 17b-HSD10 抗体
  • 17bHSD10 抗体
  • ABAD 抗体
  • Ads9 抗体
  • CAMR 抗体
  • DUPXp11.22 抗体
  • ERAB 抗体
  • Hadh2 抗体
  • HCD2 抗体
  • hsd10 抗体
  • HSD17B10 抗体
  • im:6899159 抗体
  • MHBD 抗体
  • MRPP2 抗体
  • MRX17 抗体
  • MRX31 抗体
  • MRXS10 抗体
  • SCHAD 抗体
  • SDR5C1 抗体
  • wu:fj61f03 抗体
  • zgc:101605 抗体

Protein level used designations for HSD17B10

hydroxysteroid (17-beta) dehydrogenase 10 , 3-hydroxyacyl-CoA dehydrogenase type-2 , hydroxyacyl-Coenzyme A dehydrogenase, type II , 3-hydroxy-2-methylbutyryl-CoA dehydrogenase , AB-binding alcohol dehydrogenase , amyloid-beta peptide binding alcohol dehydrogenase , endoplasmic reticulum-associated amyloid beta-peptide-binding protein , mitochondrial RNase P subunit 2 , mitochondrial ribonuclease P protein 2 , short chain L-3-hydroxyacyl-CoA dehydrogenase type 2 , short chain dehydrogenase/reductase family 5C, member 1 , short chain type dehydrogenase/reductase XH98G2 , 17-beta-HSD 10 , 17-beta-hydroxysteroid dehydrogenase 10 , 3-hydroxyacyl-CoA dehydrogenase type II , hydroxyacyl-Coenzyme A dehydrogenase type II , mitochondrial RNase P protein 2 , type II HADH , amyloid beta-peptide binding protein , short chain L-3-hydroxyacyl-CoA dehydrogenase , hydroxyacyl-Coenzyme A dehydrogenase, type II hydroxyacyl-Coenzyme A

GENE ID SPECIES
425758 Gallus gallus
450078 Danio rerio
549265 Xenopus (Silurana) tropicalis
465649 Pan troglodytes
480930 Canis lupus familiaris
100342235 Oryctolagus cuniculus
3028 Homo sapiens
446903 Xenopus laevis
15108 Mus musculus
63864 Rattus norvegicus
281809 Bos taurus
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