anti-Growth Differentiation Factor 15 (GDF15) 抗体

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. 再加上,我们可以发GDF15 试剂盒 (81)GDF15 蛋白 (41)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
GDF15 9518 Q99988
GDF15 23886 Q9Z0J7
GDF15 29455 Q9Z0J6

antibodies-online.cn销售最多的anti-GDF15 抗体

Showing 10 out of 310 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Chimpanzee 非结合性 EIA, WB 0.1 mg Log in to see 29至35个工作日
¥4,893.43
详细
山羊 非结合性 ELISA, WB ABIN185465 (0.1µg/ml) staining of Human Prostate lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 24至29个工作日
¥9,230.97
详细
非结合性 IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti--GDF15/MIC-1 Polyclonal Antibody, Unconjugated (ABIN704561) at 1:200, followed by conjugation to the secondary antibody and DAB staining Lane 1: Human K562 lysates, Lane 2: Human A431 lysates probed with Rabbit Anti-GDF15/MIC-1 Polyclonal Antibody, Unconjugated  at 1:5000 for 90 min at 37˚C. 100 μL Log in to see 5至7个工作日
¥2,709.56
详细
HRP ELISA, WB 100 μg Log in to see 23至28个工作日
¥9,424.48
详细
HRP ELISA, WB Western blot using affinity purified anti-NAG-1/GDF15 (C-terminal) antibody shows detection NAG-1 purified from CHO cells as a 14 kDa band corresponding to monomer and a 28 kDa band corresponding to dimerized NAG-1. Samples were electro-phoresed on a 4-20% gradient gel under reducing conditions. Lane 1 shows NAG-1 detection. Lane 2 shows reactivity is blocked when this antibody is pre-incubated with the immunizing peptide prior to Western blotting. 100 μg Log in to see 23至28个工作日
¥9,424.48
详细
Biotin ELISA, WB Western blot using affinity purified anti-NAG-1/GDF15 (C-terminal) antibody shows detection NAG-1 purified from CHO cells as a 14 kDa band corresponding to monomer and a 28 kDa band corresponding to dimerized NAG-1. Samples were electro-phoresed on a 4-20% gradient gel under reducing conditions. Lane 1 shows NAG-1 detection. Lane 2 shows reactivity is blocked when this antibody is pre-incubated with the immunizing peptide prior to Western blotting. 100 μg Log in to see 23至28个工作日
¥9,424.48
详细
Biotin ELISA, WB 100 μg Log in to see 23至28个工作日
¥9,424.48
详细
非结合性 WB WB Suggested Anti-GDF15 Antibody Titration: 0.2-1 ug/mlPositive Control: PANC1 cell lysate WB Suggested Anti-GDF15  Antibody Titration: 0.2-1 µg/mL  Positive Control: PANC1 cell lysate  GDF15 is strongly supported by BioGPS gene expression data to be expressed in Human PANC1 cells 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
Chimpanzee 非结合性 EIA, WB   0.1 mg Log in to see 30至37个工作日
¥3,358.40
详细
Chimpanzee 非结合性 EIA, WB   0.1 mg Log in to see 28至34个工作日
¥3,358.40
详细

通过反应活性、应用领域、克隆类型和共轭标记 GDF15 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-GDF15 抗体

  1. Human Polyclonal GDF15 Primary Antibody for IF (p), IHC (p) - ABIN704561 : Ruan, Li, Nie, Zhou, Zou: Differential expression of glycoprotein non-metastatic melanoma protein B (GPNMB) involved in trichostatin A-induced apoptosis in gastric cancer. in International journal of clinical and experimental medicine 2015 (PubMed)
    Show all 4 references for 704561

  2. Chimpanzee Polyclonal GDF15 Primary Antibody for EIA, WB - ABIN453961 : Baek, Eling: Changes in gene expression contribute to cancer prevention by COX inhibitors. in Progress in lipid research 2006 (PubMed)
    Show all 2 references for 453961

  3. Human Polyclonal GDF15 Primary Antibody for ELISA, WB - ABIN185465 : Wollmann, Goodman, Bhat-Nakshatri, Kishimoto, Goulet, Mehrotra, Morimiya, Badve, Nakshatri: The macrophage inhibitory cytokine integrates AKT/PKB and MAP kinase signaling pathways in breast cancer cells. in Carcinogenesis 2005 (PubMed)

更多抗GDF15的相互作用对抗体

Human Growth Differentiation Factor 15 (GDF15) interaction partners

  1. PPIX concentrations correlated with both growth differentiation factor (GDF) 15 (p = 0.012) and male gender (p = 0.015).

  2. Data show that growth differentiation factor 15 (GDF15) knockdown significantly inhibited the growth and metastasis of cancer stem-like sphere cells (SCs (显示 TWIST1 抗体)) through AKT (显示 AKT1 抗体)/GSK-3beta (显示 GSK3b 抗体)/beta-catenin (显示 CTNNB1 抗体) pathway suppression.

  3. epithelial restitution was promoted by enhanced NAG-1 expression and subsequent enterocyte locomotion during the early wound-healing process

  4. serum GDF15 may be a useful diagnostic and prognostic biomarker for colorectal cancer.

  5. These findings highlight an important contribution of GDF15 in promoting airway epithelial senescence upon cigarette smoke exposure.

  6. The results of this study, including a robust induction of GDF-15 expression by several external factors known to elevate IOP, and rGDF-15-induced increase in contractility, cell adhesion, and the levels of ECM (显示 MMRN1 抗体) proteins and alphaSMA (显示 ACTA2 抗体) in TM cells

  7. GDF-15 captures distinct aspects of cardiovascular disease development, progression, and prognosis, which are not represented by clinical risk predictors and other biomarkers. The usefulness of GDF-15 to guide management decisions and discover new treatment targets should be further explored.

  8. In stable Coronary Heart Disease, GDF-15 was independently associated with cardiovascular (CV), non-CV, and cancer mortality, as well as with MI and stroke. When also adjusting for other prognostic biomarkers, the associations to all fatal and nonfatal events were maintained except for MI. Information on GDF-15, therefore, might be helpful when assessing the risk of adverse outcomes in patients with stable CHD (显示 CHDH 抗体).

  9. Impaired glucose tolerance is associated with increased GDF-15 levels even in the absence of anemia

  10. GDF15 is a potent mitohormetic signal that safeguards against the onset of obesity and insulin (显示 INS 抗体) resistance.

Mouse (Murine) Growth Differentiation Factor 15 (GDF15) interaction partners

  1. This is the first study defining the role of Mic-1/Gdf15 in a number of behavioural domains.

  2. epithelial restitution was promoted by enhanced NAG-1 expression and subsequent enterocyte locomotion during the early wound-healing process

  3. both GDF-15 and TGF-beta1 (显示 TGFB1 抗体) counteract chemokine (显示 CCL1 抗体)-induced integrin activation on neutrophils via the ALK-5 (显示 TGFBR1 抗体)/TGF-betaRII heterodimer.

  4. GDF15 is a potent mitohormetic signal that safeguards against the onset of obesity and insulin (显示 INS 抗体) resistance.

  5. The aim of this study was to identify the role of endogenous Gdf-15 in the MPTP (显示 PTPN2 抗体) (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse model of Parkinson's disease (PD) by comparing Gdf-15 (+/+) and Gdf-15 (-/-) mice.

  6. The results of this study indicated the importance of Gdf-15 in promoting survival of DAergic neurons and regulating the inflammatory response post 6-OHDA lesion.

  7. endogenous Growth/differentiation factor-15 is beneficial for axon regeneration following sciatic nerve crush

  8. repeated cisterna magna administration of human umbilical cord blood-derived mesenchymal stem cells enhanced endogenous adult hippocampal neurogenesis and synaptic activity through a paracrine factor of GDF-15

  9. Levels of GDF-15 mRNA increased 2 h after induction of ventilator-induced lung injury in WT lungs. Non-hematopoietic cells are the main source of GDF-15. GDF-15 is required for platelet-leukocyte interactions during ventilator-induced lung injury.

  10. hNAG-1 appears to be a novel therapeutic target in preventing and treating obesity and insulin (显示 INS 抗体) resistance.

GDF15 抗原简介

蛋白简介

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.

Gene names and symbols associated with GDF15

  • growth differentiation factor 15 (GDF15) 抗体
  • growth differentiation factor 15 (Gdf15) 抗体
  • GDF-15 抗体
  • GDF15 抗体
  • MIC-1 抗体
  • MIC1 抗体
  • NAG-1 抗体
  • PDF 抗体
  • PLAB 抗体
  • PTGFB 抗体
  • SBF 抗体

Protein level used designations for GDF15

growth differentiation factor 15 , NRG-1 , NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1 , NSAID-activated gene 1 protein , NSAID-regulated gene 1 protein , PTGF-beta , growth/differentiation factor 15 , macrophage inhibitory cytokine 1 , placental TGF-beta , placental bone morphogenetic protein , prostate differentiation factor , GDF-15 , macrophage inhibiting cytokine-1

GENE ID SPECIES
719466 Macaca mulatta
9518 Homo sapiens
23886 Mus musculus
29455 Rattus norvegicus
468770 Pan troglodytes
100718010 Cavia porcellus
100379630 Sus scrofa
484822 Canis lupus familiaris
618677 Bos taurus
100913168 Ovis aries
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