anti-Chromobox Homolog 8 (CBX8) 抗体

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. 再加上,我们可以发CBX8 蛋白 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CBX8 30951 Q9QXV1
CBX8 57332 Q9HC52
CBX8 303731  
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antibodies-online.cn销售最多的anti-CBX8 抗体

Showing 10 out of 154 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-CBX8 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:12500<br><b>Positive Control: </b>COLO205 cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB <b>WB Suggested Anti-CBX8 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB <b>WB Suggested Anti-CBX8 Antibody Titration: </b>2.5ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-CBX8 <br /> Antibody Titration: 2.5 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Jurkat cell lysate 100 μL Log in to see 2至3个工作日
$229.00
详细
非结合性 EIA, IHC (p), WB 0.4 mL Log in to see 6至8个工作日
$390.50
详细
非结合性 EIA, WB <span>CBX8 Antibody (Center) western blot analysis in mouse liver tissue lysates (35µg/lane).This demonstrates the CBX8 antibody detected the CBX8 protein (arrow).</span> 0.4 mL Log in to see 6至8个工作日
$390.50
详细
非结合性 IHC (p), WB The anti-CBX8 C-term Pab (ABIN389089) is used in Western blot to detect CBX8 in mouse kidney tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10至11个工作日
$324.50
详细
山羊 非结合性 ELISA, WB ABIN334369 (0.1µg/ml) staining of K562 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6至7个工作日
$326.89
详细
小鼠 非结合性 FACS, ELISA, WB 100 μg Log in to see 2至3个工作日
$430.10
详细
非结合性 IP, WB Western Blot: Cbx8 Antibody  - Detection of Human CBX8 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa and 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-CBX8 antibody  used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds. 100 μL Log in to see 7至9个工作日
$486.94
详细
小鼠 非结合性 WB CBX8 Antibody (Center) (ABIN658577) western blot analysis in mouse liver tissue lysates (35 µg/lane). This demonstrates the CBX8 antibody detected the CBX8 protein (arrow). 400 μL Log in to see 10至11个工作日
$324.50
详细

通过反应活性、应用领域、克隆类型和共轭标记 CBX8 抗体

特性 应用范围 宿主 克隆类型 标记
Mouse (Murine)
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Rat (Rattus)
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引用最多的anti-CBX8 抗体

  1. Human Polyclonal CBX8 Primary Antibody for IP, WB - ABIN258057 : Maertens, El Messaoudi-Aubert, Elderkin, Hiom, Peters: Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor. in The EMBO journal 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal CBX8 Primary Antibody for FACS, ELISA - ABIN1724765 : Dietrich, Bracken, Trinh, Schjerling, Koseki, Rappsilber, Helin, Hansen: Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus. in The EMBO journal 2007 (PubMed)

更多抗CBX8的相互作用对抗体

Mouse (Murine) Chromobox Homolog 8 (CBX8) interaction partners

  1. Cbx8 associates with non-PRC1 (显示 PRC1 抗体) complexes containing the H3K4 methyltransferase complex component WDR5 (显示 WDR5 抗体), which together regulate Notch (显示 NOTCH1 抗体) gene expression.

  2. CBX8 plates roles in epigenetic regulation in DNA damage response.

  3. Cbx8 is upregulated and recruited to activated genes during embryonic stem cell differentiation.

  4. CBX8 plays an essential role in MLL (显示 MLL 抗体)-AF9 (显示 MLLT3 抗体) transcriptional regulation and leukemogenesis.

  5. Pcl2 (显示 MTF2 抗体)-PRC2 facilitates both PRC2 recruitment to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells.

  6. Huntingtin (显示 HTT 抗体) is a novel stimulator of polycomb (显示 CBX2 抗体) repressive complex 2.

Human Chromobox Homolog 8 (CBX8) interaction partners

  1. The data suggest that high expression of CBX8 plays a critical oncogenic role in aggressiveness of urothelial carcinoma cells of the bladder through promoting cancer cell proliferation by repressing the p53 (显示 TP53 抗体) pathway, and CBX8 could be used as a novel predictor for muscle invasive bladder cancer patients.

  2. CBX8 binds to H3K27me3 at bivalent promoters during germinal center formation, and recruits a novel PRC1 (显示 PRC1 抗体)-BCOR (显示 BCOR 抗体) complex at BCL6 (显示 BCL6 抗体) binding sites to specifically silence genes in the germinal center and promote lymphomagenesis

  3. CBX8 plates roles in epigenetic regulation in DNA damage response.

  4. IGF1 (显示 IGF1 抗体) can promote the colon cancer cell line, HCT116 cell, proliferation via promoting Cbx8 expression

  5. The difference in the SUZ12 and CBX8 genes expression were significantly divergent between tumors and their marginal tissues.

  6. These data suggest that CBX8 modulates SIPS through the RB-E2F1 pathway in CML cells and provide important insight into its application in CML treatment.

  7. Low CBX8 expression was associated with distant metastasis in colorectal cancer.

  8. CBX8 might emerge as an oncogene (显示 RAB1A 抗体) for promoting the proliferation of tumor cells and raising the resistance of neoplasms to chemotherapy.

  9. The presence of CBX8-GFP in the same focus had a minor impact on BMI1 and RING1 recovery kinetics.

  10. Interaction with CBX8 precludes AF9 (显示 MLLT3 抗体)-DOT1L (显示 DOT1L 抗体) binding.

CBX8 抗原简介

蛋白简介

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Gene names and symbols associated with anti-Chromobox Homolog 8 (CBX8) 抗体

  • chromobox 8 (cbx8) 抗体
  • chromobox 8 (CBX8) 抗体
  • chromobox 8 (Cbx8) 抗体
  • chromobox 8 S homeolog (cbx8.S) 抗体
  • chromobox homolog 8a (Pc class homolog, Drosophila) (cbx8a) 抗体
  • cbx8 抗体
  • MGC147589 抗体
  • PC3 抗体
  • RC1 抗体

Protein level used designations for anti-Chromobox Homolog 8 (CBX8) 抗体

chromobox homolog 8 , chromobox protein homolog 8 , mPc3 , polycomb 3 homolog , Pc class 3 homolog , chromobox homolog 8 (Pc class homolog, Drosophila) , polycomb 3 , rectachrome 1 , chromobox-like protein 8 , chromobox homolog 8 (Pc class homolog) , chromobox homolog 8a

GENE ID SPECIES
779897 Xenopus (Silurana) tropicalis
100604409 Nomascus leucogenys
30951 Mus musculus
57332 Homo sapiens
608591 Canis lupus familiaris
506458 Bos taurus
303731 Rattus norvegicus
496172 Xenopus laevis
100514536 Sus scrofa
422084 Gallus gallus
100150672 Danio rerio
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