anti-BR Serine/threonine Kinase 1 (BRSK1) 抗体

Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication. 再加上,我们可以发BRSK1 蛋白 (7)BRSK1 试剂盒 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
BRSK1 84446 Q8TDC3
BRSK1 381979 Q5RJI5
BRSK1 499073 B2DD29

antibodies-online.cn销售最多的anti-BRSK1 抗体

Showing 10 out of 134 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB 100 μL Log in to see 5至7个工作日
¥20,898.73
详细
非结合性 EIA, WB 0.4 mL Log in to see 29至35个工作日
¥4,086.26
详细
非结合性 IHC (p), WB KIAA1811 Antibody (S685) (ABIN652432) western blot analysis in mouse liver tissue lysates (35 µg/lane).This demonstrates the KIAA1811 antibody detected the KIAA1811 protein (arrow). BRSK1 Antibody (C-term) (ABIN652432)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 5至8个工作日
¥2,325.14
详细
非结合性 IHC (p), WB 50 μg Log in to see 29至35个工作日
¥5,095.23
详细
小鼠 非结合性 WB BRSK1 Antibody (Center) (ABIN1881121) western blot analysis in mouse brain tissue lysates (35 µg/lane). This demonstrates the BRSK1 antibody detected the BRSK1 protein (arrow). 400 μL Log in to see 32至37个工作日
¥2,875.04
详细
非结合性 IF, IHC (p), WB Brain, cortex 50 μg Log in to see 29至35个工作日
¥4,324.07
详细
非结合性 IHC (p), WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with BRSK1 antibody ABIN214287 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 29至35个工作日
¥4,324.07
详细
非结合性 IHC (p), WB 0.1 mg Log in to see 26至31个工作日
¥3,105.26
详细
非结合性 ELISA, WB Western blot analysis of extracts from 293 cells, using BRSK1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 24至29个工作日
¥3,026.87
详细
非结合性 ELISA, IF, WB 100 μL Log in to see 34至38个工作日
¥4,371.67
详细

通过反应活性、应用领域、克隆类型和共轭标记 BRSK1 抗体

特性 应用范围 宿主 克隆类型 标记
Human , ,
,
,
, , , , , , , , , , , , , , , , , , ,
Mouse (Murine) , ,

,
, , , , , , , , , , , , , , , , , , ,
Rat (Rattus) , ,

,
, , , , , , , , , , , , ,

引用最多的anti-BRSK1 抗体

  1. Mouse (Murine) Polyclonal BRSK1 Primary Antibody for WB - ABIN1881121 : Alvarado-Kristensson, Rodríguez, Silió, Valpuesta, Carrera: SADB phosphorylation of gamma-tubulin regulates centrosome duplication. in Nature cell biology 2009 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal BRSK1 Primary Antibody for IHC (p), WB - ABIN303016 : Zempel, Thies, Mandelkow, Mandelkow: Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 (PubMed)

  3. Human Polyclonal BRSK1 Primary Antibody for IHC (p), WB - ABIN2477731 : Suzuki, Hyodo, Kobayashi, Aida, Urano: Characterization and localization of mRNA encoding the salmon-type gonadotrophin-releasing hormone precursor of the masu salmon. in Journal of molecular endocrinology 1992 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal BRSK1 Primary Antibody for IHC, ELISA - ABIN1001941 : Lu, Niida, Nakanishi: Human SAD1 kinase is involved in UV-induced DNA damage checkpoint function. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal BRSK1 Primary Antibody for IHC, ELISA - ABIN1001942 : Kishi, Pan, Crump, Sanes: Mammalian SAD kinases are required for neuronal polarization. in Science (New York, N.Y.) 2005 (PubMed)
    Show all 2 Pubmed References

更多抗BRSK1的相互作用对抗体

Human BR Serine/threonine Kinase 1 (BRSK1) interaction partners

  1. These results suggest that frameshift mutations of EGR1 (显示 EGR1 抗体) and BRSK1 might play a role in tumorigenesis through tumor suppressor gene inactivation in colorectal cancer and gastric cancer.

  2. BRSK1 is a novel tumor suppressor in breast cancer which inversely correlated with Jab1 (显示 COPS5 抗体) expression.

  3. Single nucleotide polymorphism in BRSK1 is associated with the length of reproductive lifespan.

  4. acts as checkpoint kinase (显示 ATR 抗体) upon DNA damage induced by UV

  5. protein phosphatase 2C (显示 PDP 抗体) is a likely candidate for catalyzing the dephosphorylation and inactivation of BRSK1/2.

  6. STRADalpha.MO25alpha complexes containing LKB1 (显示 STK11 抗体) variants were equally effective at phosphorylating and activating AMPK (显示 PRKAA1 抗体), BRSK1, and BRSK2 (显示 BRSK2 抗体)

  7. SADB kinase activity controls centrosome homeostasis by regulating phosphorylation of gamma-tubulin (显示 TUBG1 抗体).

Mouse (Murine) BR Serine/threonine Kinase 1 (BRSK1) interaction partners

  1. Structure and inhibition analysis of the mouse SAD-B C-terminal fragment

  2. At mature pre-synaptic terminals, SAD-B regulates vesicular release probability and synaptic plasticity.

  3. SAD-A (显示 BRSK2 抗体) and SAD-B kinases have multiple, sequential roles in axonal differentiation

  4. The regulation of Wee1 (显示 WEE1 抗体) by SadA (显示 BRSK2 抗体) and SadB kinases is essential for the differentiation of polarized neurons.

  5. results show that SAD-A (显示 BRSK2 抗体) and SAD-B, mammalian orthologs of a kinase needed for presynaptic differentiation in Caenorhabditis elegans, are required for neuronal polarization.

  6. Once activated, LKB1 (显示 STK11 抗体) phosphorylates and thereby activates SAD-A (显示 BRSK2 抗体) and SAD-B kinases, which are also required for neuronal polarization in the cerebral cortex.

  7. SADB kinase activity controls centrosome homeostasis by regulating phosphorylation of gamma-tubulin (显示 TUBG1 抗体).

BRSK1 抗原简介

蛋白简介

Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication. Phosphorylates CDC25B, CDC25C, MAPT/TAU, RIMS1, TUBG1, TUBG2 and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Ser-573'. Also regulates neuron polarization by mediating phosphorylation of WEE1 at 'Ser-642' in post-mitotic neurons, leading to down-regulate WEE1 activity in polarized neurons. Also acts as a positive regulator of centrosome duplication by mediating phosphorylation of gamma-tubulin (TUBG1 and TUBG2) at 'Ser-131', leading to translocation of gamma-tubulin and its associated proteins to the centrosome. Involved in the UV- induced DNA damage checkpoint response, probably by inhibiting CDK1 activity through phosphorylation and activation of WEE1, and inhibition of CDC25B and CDC25C (By similarity). In neurons, localizes to synaptic vesicles and plays a role in neurotransmitter release, possibly by phosphorylating RIMS1.

Gene names and symbols associated with BRSK1

  • BR serine/threonine kinase 1 (BRSK1) 抗体
  • BR serine/threonine kinase 1 (LOC100352646) 抗体
  • BR serine/threonine kinase 1 (Brsk1) 抗体
  • BRSK1 抗体
  • Gm1100 抗体
  • hSAD1 抗体
  • RGD1563268 抗体
  • Sad-b 抗体
  • SADB 抗体

Protein level used designations for BRSK1

BR serine/threonine kinase 1 , BR serine/threonine-protein kinase 1-like , BR serine/threonine-protein kinase 1 , SAD1 homolog , SAD1 kinase , SadB kinase short isoform , brain-selective kinase 1 , brain-specific serine/threonine-protein kinase 1 , protein kinase SAD1A , serine/threonine-protein kinase BRSK1 , serine/threonine-protein kinase SAD-B , synapses of Amphids Defective homolog 1 , serine/threonine kinase SAD-B , serine/threonine kinase SADB

GENE ID SPECIES
100055612 Equus caballus
484297 Canis lupus familiaris
700287 Macaca mulatta
100352646 Oryctolagus cuniculus
100450205 Pongo abelii
100477927 Ailuropoda melanoleuca
100610477 Pan troglodytes
84446 Homo sapiens
381979 Mus musculus
499073 Rattus norvegicus
100512610 Sus scrofa
538009 Bos taurus
anti-BRSK1 (BRSK1) 抗体 精选生产商
您还需要查找其他产品吗?