anti-Ankyrin Repeat and SOCS Box-Containing 2 (ASB2) 抗体

ASB2 encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. 再加上,我们可以发ASB2 蛋白 (4)ASB2 试剂盒 (2)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ASB2 51676 Q96Q27
ASB2 65256 Q8K0L0
ASB2 299266 Q5U2S6

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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB ASB2 Antibody (N-term)  western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the ASB2 antibody detected the ASB2 protein (arrow). 400 μL Log in to see 5至8个工作日
¥2,325.14
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非结合性 WB 200 μL Log in to see 29至35个工作日
¥5,127.12
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小鼠 非结合性 IHC, WB Immunohistochemistry: ASB2 Antibody (4C2) [NBP2-46546] - Analysis of Carcinoma of Human thyroid tissue. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120C for 3 min) Immunohistochemistry: ASB2 Antibody (4C2) [NBP2-46546] - Analysis of Carcinoma of Human prostate tissue. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120C for 3 min) 0.1 mL Log in to see 26至33个工作日
¥3,655.56
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非结合性 WB Western blot analysis of Asb-2 using ABIN252587 at 1:1,000 dilution against 15 ug/lane of human spleen lysate (lane 1) and lung lysate (lane 2). Western Blot: ASB2 Antibody [ABIN2525878] - Analysis of Asb-2 in HL60 cell lysate using this antibody at 1:1000 dilution. 0.2 mL Log in to see 25至31个工作日
¥2,594.28
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小鼠 非结合性 IHC (p)   100 μL Log in to see 29至35个工作日
¥4,989.82
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Alexa Fluor 594 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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HRP IHC (p), WB   100 μL Log in to see 14至17个工作日
¥3,555.98
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Cy3 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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Cy5 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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Cy5.5 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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通过反应活性、应用领域、克隆类型和共轭标记 ASB2 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-ASB2 抗体

  1. Human Polyclonal ASB2 Primary Antibody for WB - ABIN537369 : Temmerman, Ma, Borges, Kubin, Liu, Derry, Jain: Impaired dendritic-cell function in ectodermal dysplasia with immune deficiency is linked to defective NEMO ubiquitination. in Blood 2006 (PubMed)

更多抗ASB2的相互作用对抗体

Human Ankyrin Repeat and SOCS Box-Containing 2 (ASB2) interaction partners

  1. Using ASB2 conditional knockout mice.

  2. Phosphorylation of serine 323 of ASB2 alpha by Erk (显示 EPHB2 抗体) kinases is critical for ASB2alpha-mediated degradation of FLNA (显示 FLNA 抗体).

  3. data therefore reveal ubiquitin acceptor sites in FLNa (显示 FLNA 抗体) and establish that ASB2alpha-mediated effects on cell spreading are due to loss of filamins.

  4. Data show that neither endogenous nor exogenously expressed ASB2alpha induces degradation of JAK (显示 JAK3 抗体) proteins in hematopoietic cells

  5. A model whereby ASB2 contributes to hematopoietic differentiation, in part, through MLL (显示 MLL 抗体) degradation and HOX (显示 MSH2 抗体) gene down-regulation.

  6. By shifting monomeric E3 ligase complexes to dimeric forms through activation of Asb2 transcription, Notch (显示 NOTCH1 抗体) could effectively control the turnover of a variety of substrates and it exerts diverse effects on cell proliferation and differentiation.

  7. ASB2 may regulate hematopoietic cell differentiation by modulating cell spreading and actin remodeling through targeting of filamins A and B for degradation.

Mouse (Murine) Ankyrin Repeat and SOCS Box-Containing 2 (ASB2) interaction partners

  1. This study identifies desmin (显示 DES 抗体) as a new Asb2b target for proteasomal degradation in cardiomyocytes and suggests that accumulation of desmin (显示 DES 抗体) could contribute to UPS impairment in Hypertrophic cardiomyopathy mice and patients

  2. ASB2(-/-) immature dendritic cells exhibit reduced matrix-degrading function leading to defective migration.

  3. ASB2beta is part of an active E3 ubiquitin ligase (显示 MUL1 抗体) complex and targets the actin-binding protein (显示 PFN1 抗体) filamin B (显示 FLNB 抗体) for proteasomal degradation.

ASB2 抗原简介

蛋白简介

This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with ASB2

  • ankyrin repeat and SOCS box containing 2 (ASB2) 抗体
  • ankyrin repeat and SOCS box-containing 2 (ASB2) 抗体
  • ankyrin repeat and SOCS box-containing 2 (Asb2) 抗体
  • 1110008E15Rik 抗体
  • ASB-2 抗体
  • ASB2 抗体

Protein level used designations for ASB2

ankyrin repeat and SOCS box-containing 2 , ankyrin repeat and SOCS box protein 2-like , ankyrin repeat and SOCS box protein 2 , ankyrin repeat and SOCS box-containing protein 2a , ASB-2 , ankyrin repeat and SOCS box-containing protein 2 , ankyrin repeat-containing SOCS box protein 2

GENE ID SPECIES
100064381 Equus caballus
423428 Gallus gallus
467538 Pan troglodytes
490836 Canis lupus familiaris
699882 Macaca mulatta
100227715 Taeniopygia guttata
100385735 Callithrix jacchus
100451651 Pongo abelii
51676 Homo sapiens
539244 Bos taurus
65256 Mus musculus
299266 Rattus norvegicus
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