ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13) ELISA试剂盒

ADAMTS13 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. 再加上,我们可以发ADAMTS13 抗体 (101)ADAMTS13 蛋白 (6)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
ADAMTS13 11093 Q76LX8
ADAMTS13 279028 Q769J6
ADAMTS13 102554393  
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0.127 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13至16个工作日
$419.37
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大鼠 15.6 pg/mL 62.5-4000 pg/mL Typical standard curve 96 Tests Log in to see 13至16个工作日
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小鼠 19.5 pg/mL 78-5000 pg/mL   96 Tests Log in to see 15至18个工作日
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豚鼠 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15至18个工作日
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0.625-40 ng/mL   96 Tests Log in to see 2至3个工作日
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0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15至18个工作日
$707.14
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0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15至18个工作日
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0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15至18个工作日
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0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12至14个工作日
$638.00
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引用最多的ADAMTS13 ELISA试剂盒

  1. Human ADAMTS13 ELISA Kit for Sandwich ELISA - ABIN417448 : Tati, Kristoffersson, Manea Hedström, Mörgelin, Wieslander, van Kooten, Karpman: Neutrophil Protease Cleavage of Von Willebrand Factor in Glomeruli - An Anti-thrombotic Mechanism in the Kidney. in EBioMedicine 2017 (PubMed)

适于 ADAMTS13 相互作用对的更多 ELISA 试剂盒

Human ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13) interaction partners

  1. As folding stability was progressively disrupted, proteolysis by ADAMTS13 increased. Due to the range of folding stabilities and wide distribution of VWF (显示 VWF ELISA试剂盒) A2 domain mutations studied, we conclude that these mutations disrupt regulated folding of the VWF (显示 VWF ELISA试剂盒) A2 domain

  2. The 'closed' conformation of ADAMTS-13 restricts its specificity and protects against fibrinogenolysis

  3. Our results indicate that the secondary TMA syndrome and its poor outcome is characterized by relative ADAMTS13 deficiency, inflammation, and complement activation with consumption via the classical and alternative pathways.

  4. Diagnosis of thrombotic thrombocytopenic purpura among patients with ADAMTS13 Activity 10%-20.

  5. Rare genetic variants in the ADAMTS13 on Willebrand factor-binding domain contribute to pediatric stroke.

  6. No correlation was found between VWF (显示 VWF ELISA试剂盒)/ADAMTS13 and infarct size in patients. Patients suffering from intramyocardial hemorrhage had significantly higher VWF (显示 VWF ELISA试剂盒) activity and lower ADAMTS13 activity. Intracoronary administration of rADAMTS13 did not decrease infarct size or IMH in a porcine model of myocardial ischaemia-reperfusion, disputing the idea that the imbalance in ADAMTS13 and VWF (显示 VWF ELISA试剂盒) as the cause of no reflow.

  7. both in acute and chronic cerebrovascular disease patients, ADAMTS13 levels were significantly decreased, with the lowest ADAMTS13 levels found in acute stroke patients. This difference was even more distinct when the ratio of VWF:ADAMTS13 was considered. These results demonstrate the potentially important involvement of the VWF (显示 VWF ELISA试剂盒)/ADAMTS13 axis in ischemic stroke.

  8. Placental trophoblasts and villous vessel endothelial cells produce a full-length and functional ADAMTS13 protease. Placental expression of ADAMTS13 exhibits a dynamic change during pregnancy, which seems to be inhibited in late pregnancy and in patients with severe preeclampsia.

  9. ADAMTS13 activity appears to be an independent risk factor for incident prediabetes and type 2 diabetes.

  10. both anti-ADAMTS13 IgG antibody and ADAMTS13 antigen levels correlate with outcome in thrombotic thrombocytopenic purpura with increased cardiac and neurological involvement and increased mortality.

Mouse (Murine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13) interaction partners

  1. results suggest that ADAMTS13 controls key steps of ischemic vascular remodeling and that recombinant ADAMTS13 is a putative therapeutic avenue for promoting stroke recovery.

  2. ADAMTS13 retards progression of diabetic nephropathy, most likely by inhibiting VWF (显示 VWF ELISA试剂盒)-dependent intrarenal thrombosis.

  3. administration of ADAMTS13 5 minutes after occlusion dose-dependently dissolved these t-PA-resistant thrombi resulting in fast restoration of MCA patency and consequently reduced cerebral infarct sizes

  4. Sleeping beauty transposon-mediated gene therapy achieved sustained expression of transgene ADAMTS13 and long-term prophylaxis against congenital thrombotic thrombocytopenic purpura in Adamts13(-/-) mice.

  5. Results also suggest that Toxoplasma gondii-mediated apoptosis might play a pivotal role and a different type of role in the mechanism of neurodegeneration and neuropathology in the process of toxoplasma encephalitis. Furthermore, expression of ADAMTS-13 might give an idea of the progress and is critical for diagnosis of this disease.

  6. Letter: deficiency of ADAMTS13 results in increased formation of venous thrombosis in mice.

  7. ADAMTS13 substrate specificity

  8. Data indicate that the p.D187H mutation impairs ADAMTS13 activity and secretion and may contribute to thrombotic thrombocytopenic purpura.

  9. Data show that metalloendopeptidase (显示 THOP1 ELISA试剂盒) ADAMTS13 does not directly promote development of adipose tissue.

  10. findings provide further evidence on the pathophysiological role for the ADAMTS13/VWF (显示 VWF ELISA试剂盒) axis in atherosclerosis

ADAMTS13 抗原简介

Antigen Summary

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.

Gene names and symbols associated with ADAMTS13

  • ADAM metallopeptidase with thrombospondin type 1 motif 13 (ADAMTS13) 抗体
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 (Adamts13) 抗体
  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (adamts13) 抗体
  • ADAM metallopeptidase with thrombospondin type 1 motif 12 (ADAMTS12) 抗体
  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (Adamts13) 抗体
  • ADAM metallopeptidase with thrombospondin type 1 motif 13 (Adamts13) 抗体
  • ADAM-TS13 抗体
  • ADAMTS-13 抗体
  • ADAMTS12 抗体
  • ADAMTS13 抗体
  • C9orf8 抗体
  • Gm710 抗体
  • vWF-CP 抗体
  • VWFCP 抗体

Protein level used designations for ADAMTS13

ADAM metallopeptidase with thrombospondin type 1 motif, 13 , A disintegrin and metalloproteinase with thrombospondin motifs 13 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13 , vWF-cleaving protease , von Willebrand factor-cleaving protease , ADAM-TS 13 , ADAM-TS13 , ADAMTS-13 , ADAMTS13 isoform IAP-b , vWF-CP mRNA for von Willebrand factor-cleaving , ADAM metallopeptidase with thrombospondin type 1 motif, 13 isoform 1 preproprotein-like , ADAM metallopeptidase with thrombospondin type 1 motif, 12 , A disintegrin and metalloproteinase with thrombospondin motifs 12 , A disintegrin and metalloproteinase with thrombospondin motifs 13-like , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13

GENE ID SPECIES
100069281 Equus caballus
11093 Homo sapiens
279028 Mus musculus
532272 Bos taurus
100320289 Danio rerio
479369 Canis lupus familiaris
427428 Gallus gallus
100068281 Equus caballus
461952 Pan troglodytes
525276 Bos taurus
701750 Macaca mulatta
100404947 Callithrix jacchus
100343027 Oryctolagus cuniculus
100481099 Ailuropoda melanoleuca
100226372 Taeniopygia guttata
100630922 Canis lupus familiaris
102554393 Rattus norvegicus
100727045 Cavia porcellus
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