ZAP70 抗体
(zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| ZAP70 抗体 (pTyr493) (FITC) | 人 | 兔 Polyclonal |
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| ZAP70 抗体 (pTyr493) (Biotin) | 人 | 兔 Polyclonal |
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| ZAP70 抗体 (pTyr493) (Cy3) | 人 | 兔 Polyclonal |
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| ZAP70 抗体 (pTyr493) (Cy5) | 人 | 兔 Polyclonal |
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| ZAP70 抗体 (pTyr315, pTyr319) (HRP) | 人 | 兔 Polyclonal |
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| ZAP70 抗体 (pTyr493) (HRP) | 人 | 兔 Polyclonal |
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| ZAP70 抗体 (AA 337-600) | 人 | 兔 Polyclonal |
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| ZAP70 抗体 (AA 1-254) | 人 | 小鼠 Monoclonal |
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| ZAP70 抗体 (AA 247-382) | 人 | 小鼠 Monoclonal |
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| Recombinant ZAP70 抗体 (AA 247-382) | 人 | 兔 Monoclonal |
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| ZAP70 抗体 (AA 247-382) | 人 | 小鼠 Monoclonal |
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| Recombinant ZAP70 抗体 (AA 247-382) | 人 | 小鼠 Monoclonal |
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| Recombinant ZAP70 抗体 (AA 247-382) | 人 | 小鼠 Monoclonal |
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|
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| Recombinant ZAP70 抗体 (AA 247-382) | 人 | 兔 Monoclonal |
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| ZAP70 抗体 (AA 247-382) (iFluor™488) | 人 | 小鼠 Monoclonal |
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| ZAP70 抗体 (AA 247-382) | 人 | 小鼠 Monoclonal |
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| ZAP70 抗体 (AA 247-382) (FITC) | 人 | 小鼠 Monoclonal |
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| ZAP70 抗体 (pTyr319) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ZAP70 抗体 (pTyr315) | 人, 小鼠 | 兔 Polyclonal |
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| ZAP70 抗体 (pTyr493) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- pTyr493
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- pTyr493
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy3
- 抗体亚型
- IgG
- 抗原表位
- pTyr493
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy5
- 抗体亚型
- IgG
- 抗原表位
- pTyr493
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- pTyr315, pTyr319
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- pTyr493
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 337-600
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2F3-2
- 标记
- unconjugated
- 抗体亚型
- IgG2a, kappa
- 抗原表位
- AA 1-254
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- ZAP70-2035
- 标记
- unconjugated
- 抗体亚型
- IgG1, kappa
- 抗原表位
- AA 247-382
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- ZAP70-6492R
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG, kappa
- 抗原表位
- AA 247-382
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- ZAP70-2046
- 标记
- unconjugated
- 抗体亚型
- IgG2a, kappa
- 抗原表位
- AA 247-382
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- rZAP70-2046
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG1, kappa
- 抗原表位
- AA 247-382
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- rZAP70-2046
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG1, kappa
- 抗原表位
- AA 247-382
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- ZAP70-6492R
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG, kappa
- 抗原表位
- AA 247-382
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- 质量等级
- GMP Grade
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- C-D12
- 标记
- iFluor™488
- 抗体亚型
- IgG1, kappa
- 抗原表位
- AA 247-382
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- 质量等级
- GMP Grade
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- C-D12
- 标记
- unconjugated
- 抗体亚型
- IgG1, kappa
- 抗原表位
- AA 247-382
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- 质量等级
- GMP Grade (Analyte)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- C-D12
- 标记
- FITC
- 抗体亚型
- IgG1, kappa
- 抗原表位
- AA 247-382
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pTyr319
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pTyr315
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pTyr493
Latest Publications for our ZAP70 抗体
: "Fibulin-3 may improve vascular health through inhibition of MMP-2/9 and oxidative stress in spontaneously hypertensive rats." in: Molecular medicine reports, Vol. 13, Issue 5, pp. 3805-12, (2017) (PubMed).
: "Hypertensive vascular remodeling was inhibited by Xuezhikang through the regulation of Fibulin-3 and MMPs in spontaneously hypertensive rats." in: International journal of clinical and experimental medicine, Vol. 8, Issue 2, pp. 2118-27, (2015) (PubMed).
: "PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011) (PubMed).
: "ZAP-70 enhances B-cell-receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells." in: Blood, Vol. 109, Issue 5, pp. 2032-9, (2007) (PubMed).
: "CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mobilization." in: European journal of immunology, Vol. 38, Issue 1, pp. 40-7, (2007) (PubMed).
: "T cell activation-induced CrkII binding to the Zap70 protein tyrosine kinase is mediated by Lck-dependent phosphorylation of Zap70 tyrosine 315." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 12, pp. 8123-32, (2005) (PubMed).
: "Immunohistochemical analysis of ZAP-70 expression in B-cell lymphoid neoplasms." in: The Journal of pathology, Vol. 205, Issue 4, pp. 507-13, (2005) (PubMed).
: "[Everything you ever wanted to know about ZAP-70]." in: Médecine sciences : M/S, Vol. 21, Issue 2, pp. 150-5, (2005) (PubMed).
: "In vivo correction of ZAP-70 immunodeficiency by intrathymic gene transfer." in: The Journal of clinical investigation, Vol. 115, Issue 8, pp. 2287-95, (2005) (PubMed).
: "Evidence for the involvement of tyrosine kinase ZAP 70 in nuclear retinoid receptor-dependent transactivation in T lymphocytes." in: The Journal of biological chemistry, Vol. 280, Issue 40, pp. 34152-8, (2005) (PubMed).
: "Hypertensive vascular remodeling was inhibited by Xuezhikang through the regulation of Fibulin-3 and MMPs in spontaneously hypertensive rats." in: International journal of clinical and experimental medicine, Vol. 8, Issue 2, pp. 2118-27, (2015) (PubMed).
: "PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011) (PubMed).
: "ZAP-70 enhances B-cell-receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells." in: Blood, Vol. 109, Issue 5, pp. 2032-9, (2007) (PubMed).
: "CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mobilization." in: European journal of immunology, Vol. 38, Issue 1, pp. 40-7, (2007) (PubMed).
: "T cell activation-induced CrkII binding to the Zap70 protein tyrosine kinase is mediated by Lck-dependent phosphorylation of Zap70 tyrosine 315." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 12, pp. 8123-32, (2005) (PubMed).
: "Immunohistochemical analysis of ZAP-70 expression in B-cell lymphoid neoplasms." in: The Journal of pathology, Vol. 205, Issue 4, pp. 507-13, (2005) (PubMed).
: "[Everything you ever wanted to know about ZAP-70]." in: Médecine sciences : M/S, Vol. 21, Issue 2, pp. 150-5, (2005) (PubMed).
: "In vivo correction of ZAP-70 immunodeficiency by intrathymic gene transfer." in: The Journal of clinical investigation, Vol. 115, Issue 8, pp. 2287-95, (2005) (PubMed).
: "Evidence for the involvement of tyrosine kinase ZAP 70 in nuclear retinoid receptor-dependent transactivation in T lymphocytes." in: The Journal of biological chemistry, Vol. 280, Issue 40, pp. 34152-8, (2005) (PubMed).
Aliases for ZAP70 抗体
zeta chain of T-cell receptor associated protein kinase 70 (ZAP70) 抗体putative tyrosine-protein kinase zap-70 (Smp_149470) 抗体
zeta-chain (TCR) associated protein kinase (Zap70) 抗体
zeta chain of T cell receptor associated protein kinase 70 (Zap70) 抗体
zeta-chain (TCR) associated protein kinase 70kDa (ZAP70) 抗体
zeta chain of T cell receptor associated protein kinase 70kDa L homeolog (zap70.L) 抗体
zeta chain of T cell receptor associated protein kinase 70kDa (zap70) 抗体
zeta chain of T cell receptor associated protein kinase 70 (ZAP70) 抗体
tyrosine-protein kinase ZAP-70 (LOC707555) 抗体
tyrosine-protein kinase ZAP-70 (ZAP70) 抗体
tyrosine-protein kinase ZAP-70 (LOC100342021) 抗体
tyrosine-protein kinase ZAP-70 (LOC100390922) 抗体
tyrosine-protein kinase ZAP-70 (LOC100542877) 抗体
zeta-chain (TCR) associated protein kinase 70kDa (Zap70) 抗体
zeta-chain (TCR) associated protein kinase (zap70) 抗体
70kDa 抗体
AI327364 抗体
MGC80670 抗体
MGC88962 抗体
mrtle 抗体
mur 抗体
SRK 抗体
Srk 抗体
STCD 抗体
STD 抗体
TZK 抗体
ZAP-70 抗体
zap70 抗体
ZAP70 抗体
zgc:110383 抗体
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