This gene encodes a member of the WD-protein subfamily. This protein shares a high sequence identity to mouse and chick proteins. It contains several WD-repeats spanning most of the protein and an SOCS box in the C-terminus. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Choi, Seo, Kim, Sung, Ahn, Park, Lee, Choi: "Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1." in: The Journal of biological chemistry, Vol. 283, Issue 8, pp. 4682-9, (2008) (PubMed).