(Wingless-Type MMTV Integration Site Family, Member 16 (WNT16))
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen. [provided by RefSeq, Jul 2008].
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McWhirter, Neuteboom, Wancewicz, Monia, Downing, Murre: "Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 20, pp. 11464-9, (1999) (PubMed).
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Cadigan, Nusse: "Wnt signaling: a common theme in animal development." in: Genes & development, Vol. 11, Issue 24, pp. 3286-305, (1998) (PubMed).
Aliases for WNT16 抗体
Wnt family member 16 (WNT16) 抗体 wingless-type MMTV integration site family, member 16 (wnt16) 抗体 Wnt family member 16 (wnt16) 抗体 wingless-type MMTV integration site family, member 16 (Wnt16) 抗体 Wnt family member 16 (Wnt16) 抗体 E130309I19Rik 抗体 zgc:77293 抗体