WFDC2 蛋白
(WAP Four-Disulfide Core Domain 2 (WFDC2))
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008].
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Latest Publications for our WFDC2 蛋白
: "Human epididymis protein 4 antigen-autoantibody complexes complement cancer antigen 125 for detecting early-stage ovarian cancer." in: Cancer, (2019) (PubMed).
: "Selection of DNA aptamers for ovarian cancer biomarker HE4 using CE-SELEX and high-throughput sequencing." in: Analytical and bioanalytical chemistry, (2015) (PubMed).
: "Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis." in: Nature medicine, Vol. 19, Issue 2, pp. 227-31, (2013) (PubMed).
: "The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma." in: Cancer research, Vol. 63, Issue 13, pp. 3695-700, (2003) (PubMed).
: "A major human epididymis-specific cDNA encodes a protein with sequence homology to extracellular proteinase inhibitors." in: Biology of reproduction, Vol. 45, Issue 2, pp. 350-7, (1992) (PubMed).
: "Selection of DNA aptamers for ovarian cancer biomarker HE4 using CE-SELEX and high-throughput sequencing." in: Analytical and bioanalytical chemistry, (2015) (PubMed).
: "Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis." in: Nature medicine, Vol. 19, Issue 2, pp. 227-31, (2013) (PubMed).
: "The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma." in: Cancer research, Vol. 63, Issue 13, pp. 3695-700, (2003) (PubMed).
: "A major human epididymis-specific cDNA encodes a protein with sequence homology to extracellular proteinase inhibitors." in: Biology of reproduction, Vol. 45, Issue 2, pp. 350-7, (1992) (PubMed).
Aliases for WFDC2 蛋白
WAP four-disulfide core domain 2 (WFDC2) 蛋白WAP four-disulfide core domain 2 (wfdc2) 蛋白
WAP four-disulfide core domain 2 (Wfdc2) 蛋白
1600023A02Rik 蛋白
BE-20 蛋白
CE4 蛋白
dJ461P17.6 蛋白
EDDM4 蛋白
HE4 蛋白
re4 蛋白
si:ch211-153a8.3 蛋白
WAP5 蛋白
WFDC2 蛋白
WFDC3 蛋白
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