This gene encodes a member of the UDP-glycosyltransferase (UDPGT) family. The UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein displays activity towards several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens. [provided by RefSeq, Oct 2011].
OShaughnessy, Monteiro, Bhattacharya, Fraser, Fowler: "Steroidogenic enzyme expression in the human fetal liver and potential role in the endocrinology of pregnancy." in: Molecular human reproduction, Vol. 19, Issue 3, pp. 177-87, (2013) (PubMed).