Ubiquitin-Conjugating Enzyme E2K 抗体
(Ubiquitin-Conjugating Enzyme E2K (UBE2K))
The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
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Latest Publications for our Ubiquitin-Conjugating Enzyme E2K 抗体
: "Novel polysome messages and changes in translational activity appear after induction of adipogenesis in 3T3-L1 cells." in: BMC molecular biology, Vol. 13, pp. 9, (2012) (PubMed).: "Hip2 interacts with and destabilizes Smac/DIABLO." in: Biochemical and biophysical research communications, Vol. 397, Issue 4, pp. 718-23, (2010) (PubMed).
: "Ubiquitin-conjugating enzyme E2-25K increases aggregate formation and cell death in polyglutamine diseases." in: Molecular and cellular neurosciences, Vol. 34, Issue 1, pp. 10-9, (2007) (PubMed).
: "E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages." in: Nature structural & molecular biology, Vol. 14, Issue 10, pp. 941-8, (2007) (PubMed).
: "E2-25K mediates US11-triggered retro-translocation of MHC class I heavy chains in a permeabilized cell system." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 31, pp. 11589-94, (2006) (PubMed).
: "NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF)." in: The Journal of biological chemistry, Vol. 281, Issue 30, pp. 20749-60, (2006) (PubMed).
: "Regulation of macrophage-specific gene expression by degenerated lipoproteins." in: Electrophoresis, Vol. 21, Issue 2, pp. 338-46, (2000) (PubMed).
: "Induction of ubiquitin-conjugating enzyme by aggregated low density lipoprotein in human macrophages and its implications for atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 20, Issue 1, pp. 128-34, (2000) (PubMed).
: "Recent advances on the pathogenesis of Huntington's disease." in: Experimental neurology, Vol. 157, Issue 1, pp. 1-18, (1999) (PubMed).
: "Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme." in: The Journal of biological chemistry, Vol. 271, Issue 32, pp. 19385-94, (1996) (PubMed).
Aliases for Ubiquitin-Conjugating Enzyme E2K 抗体
ubiquitin conjugating enzyme E2 K (UBE2K) 抗体ubiquitin-conjugating enzyme E2K (Ube2k) 抗体
ubiquitin conjugating enzyme E2 K S homeolog (ube2k.S) 抗体
ubiquitin conjugating enzyme E2 K (ube2k) 抗体
ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) (ube2kb) 抗体
ubiquitin conjugating enzyme E2 K (Ube2k) 抗体
ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast) (ube2ka) 抗体
AW492011 抗体
D5Ertd601e 抗体
E2-25K 抗体
E2-25k 抗体
e2-25k 抗体
HIP2 抗体
Hip2 抗体
hip2 抗体
HYPG 抗体
Hypg 抗体
hypg 抗体
LIG 抗体
Lig 抗体
lig 抗体
UBC1 抗体
ube2k 抗体
zgc:103472 抗体
zgc:110791 抗体
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