TRIM30 抗体
(Tripartite Motif Containing 30 (Trim30))
Trans-acting factor that regulates gene expression of interleukin 2 receptor alpha chain. May affect IL2R-alpha expression through cis-acting negative regulatory elements or through competition with proteins that bind to enhancer or activator sequences. Negatively regulates Toll-like receptor (TLR)-mediated activation of NFKB by promoting degradation of TAB2 and TAB3 and preventing TRAF6 autoubiquitination. Negatively regulates production of reactive oxygen species (ROS) which inhibits activation of the NLRP3 inflammasome complex. This, in turn, regulates activation of CASP1 and subsequent cleavage of IL1B and IL18. No activity detected against a range of retroviruses including a number of lentiviruses, gammaretroviruses and betaretroviruses.
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| TRIM30 抗体 (C-Term) | 小鼠, 人 | 兔 Polyclonal |
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| TRIM30 抗体 (N-Term) | 小鼠, 大鼠, 人 | 兔 Polyclonal |
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| TRIM30 抗体 (N-Term) | 小鼠, 大鼠 | 兔 Polyclonal |
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| TRIM30 抗体 (C-Term) | 小鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 110-160, N-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 250-300, C-Term
Latest Publications for our TRIM30 抗体
: "A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models." in: Nature communications, Vol. 8, Issue 1, pp. 1164, (2018) (PubMed).
Aliases for TRIM30 抗体
tripartite motif-containing 30 (Trim30) 抗体tripartite motif-containing 30A (Trim30a) 抗体
RGD1563970 抗体
Rpt-1 抗体
Rpt1 抗体
Trim30 抗体
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