TRIM30 抗体 (N-Term)
Trim30
适用: 小鼠, 大鼠
WB, ELISA, IHC (p), IF
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all TRIM30 (Trim30) 抗体
- TRIM30 (Trim30) (Tripartite Motif Containing 30 (Trim30))
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抗原表位
- AA 110-160, N-Term
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRIM30 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- TRIM30 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- TRIM30 antibody was raised against a 21 amino acid synthetic peptide near the amino terminus of the mouse TRIM30. The immunogen is located within amino acids 110 - 160 of TRIM30.
- 亚型
- IgG
- Top Product
- Discover our top product Trim30 Primary Antibody
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anti-Tripartite Motif Containing 30 (Trim30) (C-Term) antibody
Trim30 适用: 小鼠, 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 30 (Trim30) (N-Term) antibodyTrim30 适用: 小鼠, 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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TRIM30 antibody can be used for detection of TRIM30 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- TRIM30 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- TRIM30 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- TRIM30 (Trim30) (Tripartite Motif Containing 30 (Trim30))
- 别名
- TRIM30 (Trim30 产品)
- 别名
- RGD1563970 antibody, Rpt-1 antibody, Rpt1 antibody, Trim30 antibody, tripartite motif-containing 30 antibody, tripartite motif-containing 30A antibody, Trim30 antibody, Trim30a antibody
- 背景
- TRIM30 Antibody: TRIM30 belongs to a family of the tripartite motif (TRIM) proteins involved in the regulation of cell proliferation, differentiation, development, oncogenesis, apoptosis and antiviral responses. The TRIM protein family is an expanding family of RING ('really interesting new gene') proteins, also known as RBCC proteins as they contain an RBCC motif, which comprises a RING domain, one or two B-boxes and a predicted coiled-coil region. Studies have shown that some TRIM family members are critical to innate immunity, TRIM5, TRIM19 and TRIM25, for example, have been shown to restrict viral infection. A recent study shows that TRIM30 functions as a negative modulator of the TLR signaling pathway, by targeting TAB2 and TAB3, and contributes to the inhibition of TLR-mediated NF-κ,B activation. The importance of TRIM30 in the attenuation or termination of NF-κ,B activation suggests that targeting of TAB2 and TAB3 by TRIM30alpha may be a mechanism for modulating many types of immune responses.
- 分子量
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Predicted: 107 kDa
Observed: 105 kDa - 基因ID
- 20128
- NCBI登录号
- NP_033125
- UniProt
- P15533
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