TREM2 蛋白
(Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))
This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012].
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Latest Publications for our TREM2 蛋白
: "Cerebrospinal Fluid Biomarkers in Cerebral Amyloid Angiopathy." in: Journal of Alzheimer's disease : JAD, Vol. 74, Issue 4, pp. 1189-1201, (2020) (PubMed).
: "Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroup." in: Alzheimer's research & therapy, Vol. 10, Issue 1, pp. 79, (2018) (PubMed).
: "The Alzheimer's disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathway." in: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 59, (2017) (PubMed).
: "Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroup." in: Alzheimer's research & therapy, Vol. 10, Issue 1, pp. 79, (2018) (PubMed).
: "The Alzheimer's disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathway." in: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 59, (2017) (PubMed).
Aliases for TREM2 蛋白
triggering receptor expressed on myeloid cells 2 (TREM2) 蛋白triggering receptor expressed on myeloid cells 2 (trem2) 蛋白
trem-like transcript 2 protein (LOC100228399) 蛋白
triggering receptor expressed on myeloid cells 2 (Trem2) 蛋白
trem-2 蛋白
TREM-2 蛋白
TREM-A1 蛋白
TREM-B1 蛋白
TREM2 蛋白
trem2a 蛋白
Trem2a 蛋白
trem2b 蛋白
Trem2b 蛋白
trem2c 蛋白
Trem2c 蛋白
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