(TOX High Mobility Group Box Family Member 3 (TOX3))
The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2009].
Han, Yue, Yang, Jian, Ma, Liu: "TOX3 protein expression is correlated with pathological characteristics in breast cancer." in: Oncology letters, Vol. 11, Issue 3, pp. 1762-1768, (2016) (PubMed).
Easton, Pooley, Dunning, Pharoah, Thompson, Ballinger, Struewing, Morrison, Field, Luben, Wareham, Ahmed, Healey, Bowman, Meyer, Haiman, Kolonel, Henderson, Le Marchand, Brennan, Sangrajrang et al.: "Genome-wide association study identifies novel breast cancer susceptibility loci. ..." in: Nature, Vol. 447, Issue 7148, pp. 1087-93, (2007) (PubMed).
Aliases for TOX3 抗体
TOX high mobility group box family member 3 (TOX3) 抗体 TOX high mobility group box family member 3 (tox3) 抗体 TOX high mobility group box family member 3 (Tox3) 抗体 500-9 抗体 BC052044 抗体 C230068E13 抗体 cagf9 抗体 CAGF9 抗体 TNRC9 抗体 tnrc9 抗体 Tnrc9 抗体