Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1 (By similarity).
Sperandio, Barat, Cabrita, Gargaun, Berezovski, Tremblay, de Belle: "TOE1 is an inhibitor of HIV-1 replication with cell-penetrating capability." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 26, pp. E3392-401, (2015) (PubMed).
Sperandio, Tardito, Surzycki, Latterich, de Belle: "TOE1 interacts with p53 to modulate its transactivation potential." in: FEBS letters, Vol. 583, Issue 13, pp. 2165-70, (2009) (PubMed).
Aliases for TOE1 抗体
target of EGR1, exonuclease (TOE1) 抗体 target of EGR1, member 1 (nuclear) (Toe1) 抗体 target of EGR1, member 1 (nuclear) (TOE1) 抗体 target of EGR1, exonuclease (toe1) 抗体 target of EGR1, member 1 (nuclear) (toe1) 抗体 target of EGR1, exonuclease (Toe1) 抗体 4930584N22Rik 抗体 4933424D16Rik 抗体 AI413517 抗体 si:dkey-40i22.3 抗体 TOE1 抗体