TNFSF8 抗体
(Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8))
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
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58 results
TNFSF8
适用: 小鼠
FACS, BP, Func
宿主: 兔
Chimeric
RM153
unconjugated
Recombinant Antibody
1 image
Latest Publications for our TNFSF8 抗体
: "Blocking CD30 on T Cells by a Dual Specific CAR for CD30 and Colon Cancer Antigens Improves the CAR T Cell Response against CD30- Tumors." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 27, Issue 10, pp. 1825-1835, (2019) (PubMed).: "CD117⁺ CD3⁻ CD56⁻ OX40Lhigh cells express IL-22 and display an LTi phenotype in human secondary lymphoid tissues." in: European journal of immunology, Vol. 41, Issue 6, pp. 1563-72, (2011) (PubMed).
: "Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1." in: The EMBO journal, Vol. 26, Issue 13, pp. 3086-97, (2007) (PubMed).
: "CD40 induces macrophage anti-Toxoplasma gondii activity by triggering autophagy-dependent fusion of pathogen-containing vacuoles and lysosomes." in: The Journal of clinical investigation, Vol. 116, Issue 9, pp. 2366-77, (2006) (PubMed).
: "Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis." in: The Journal of experimental medicine, Vol. 191, Issue 2, pp. 375-80, (2000) (PubMed).
: "High CD30 ligand expression by epithelial cells and Hassal's corpuscles in the medulla of human thymus." in: Blood, Vol. 91, Issue 9, pp. 3323-32, (1998) (PubMed).
: "CD30-mediated signaling promotes the development of human T helper type 2-like T cells." in: The Journal of experimental medicine, Vol. 182, Issue 6, pp. 1655-61, (1996) (PubMed).
: "CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF." in: Cell, Vol. 73, Issue 7, pp. 1349-60, (1993) (PubMed).
Aliases for TNFSF8 抗体
tumor necrosis factor (ligand) superfamily, member 8 (Tnfsf8) 抗体TNF superfamily member 8 (TNFSF8) 抗体
tumor necrosis factor superfamily member 8 (TNFSF8) 抗体
TNF superfamily member 8 (Tnfsf8) 抗体
Cd30l 抗体
CD30L 抗体
CD30LG 抗体
CD153 抗体
TNFRSF8 抗体
TNFSF8 抗体
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