TNF Receptor Superfamily, Member 6 抗体
(TNF Receptor Superfamily, Member 6 (FAS))
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. [provided by RefSeq, Mar 2011].
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312 results
FAS
适用: 人
WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc)
宿主: 兔
Polyclonal
unconjugated
FAS
适用: 人, 大鼠, 小鼠, 猴
WB, ELISA, IHC (fro), IHC (p)
宿主: 兔
Polyclonal
Biotin
Latest Publications for our TNF Receptor Superfamily, Member 6 抗体
: "EGF-mediated reduced miR-92a-1-5p controls HTR-8/SVneo cell invasion through activation of MAPK8 and FAS which in turn increase MMP-2/-9 expression." in: Scientific reports, Vol. 10, Issue 1, pp. 12274, (2020) (PubMed).: "Dietary methionine restriction reduces hepatic steatosis and oxidative stress in high-fat-fed mice by promoting H2S production." in: Food & function, Vol. 10, Issue 1, pp. 61-77, (2019) (PubMed).
: "Danshensu Decreases UVB-Induced Corneal Inflammation in an Experimental Mouse Model via Oral Administration." in: Current eye research, Vol. 43, Issue 1, pp. 27-34, (2018) (PubMed).
: "Artesunate enhances γδ T-cell-mediated antitumor activity through augmenting γδ T-cell function and reversing immune escape of HepG2 cells." in: Immunopharmacology and immunotoxicology, Vol. 40, Issue 2, pp. 107-116, (2018) (PubMed).
: "Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli." in: Respiratory research, Vol. 19, Issue 1, pp. 91, (2018) (PubMed).
: "Prior Puma Lentivirus Infection Modifies Early Immune Responses and Attenuates Feline Immunodeficiency Virus Infection in Cats." in: Viruses, Vol. 10, Issue 4, (2018) (PubMed).
: "SUMO2 modification of Aurora B and its impact on follicular development and atresia in the mouse ovary." in: International journal of molecular medicine, Vol. 41, Issue 6, pp. 3115-3126, (2018) (PubMed).
: "Inflammatory signature of cerebellar neurodegeneration during neonatal hyperbilirubinemia in Ugt1 (-/-) mouse model." in: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 64, (2017) (PubMed).
: "The Utility of Biomarkers in Osteoporosis Management." in: Molecular diagnosis & therapy, Vol. 21, Issue 4, pp. 401-418, (2017) (PubMed).
: "BRE modulates granulosa cell death to affect ovarian follicle development and atresia in the mouse." in: Cell death & disease, Vol. 8, Issue 3, pp. e2697, (2017) (PubMed).
Aliases for TNF Receptor Superfamily, Member 6 抗体
Fas cell surface death receptor (FAS) 抗体Fas (TNF receptor superfamily member 6) (Fas) 抗体
Fas cell surface death receptor (Fas) 抗体
Fas cell surface death receptor (fas) 抗体
AI196731 抗体
ALPS1A 抗体
APO-1 抗体
APO1 抗体
APT1 抗体
CD95 抗体
FAS1 抗体
FASTM 抗体
lpr 抗体
TNFR6 抗体
TNFRSF6 抗体
Tnfrsf6 抗体
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