TMED10 抗体
(Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008].
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Latest Publications for our TMED10 抗体
: "TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity." in: Nature, Vol. 440, Issue 7088, pp. 1208-12, (2006) (PubMed).: "Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2." in: Journal of neuroscience research, Vol. 77, Issue 3, pp. 309-22, (2004) (PubMed).
: "The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease." in: Trends in cell biology, Vol. 8, Issue 11, pp. 447-53, (1999) (PubMed).
Aliases for TMED10 抗体
transmembrane p24 trafficking protein 10 L homeolog (tmed10.L) 抗体transmembrane p24 trafficking protein 10 (TMED10) 抗体
transmembrane p24 trafficking protein 10 (Tmed10) 抗体
transmembrane p24 trafficking protein 10 (tmed10) 抗体
1110014C03Rik 抗体
fe06g04 抗体
p23 抗体
P24(DELTA) 抗体
p24delta1 抗体
S31I125 抗体
S31III125 抗体
Tmp-21-I 抗体
tmp21 抗体
TMP21 抗体
Tmp21 抗体
wu:fb98e10 抗体
wu:fe06g04 抗体
zgc:85681 抗体
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