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TMED10 产品

(Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))

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This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008].

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Featured TMED10 Categories

TMED10 抗体

High quality antibodies with extensive validation data.

TMED10 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TMED10 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC
Validations
  • (2)
Cat. No. ABIN1386483
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, FACS
Validations
  • (2)
Cat. No. ABIN190858
Quantity 100 μg
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6744308
Quantity 100 μL
Datasheet Datasheet

Recommended TMED10 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125477
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3137071
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3113757
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TMED10 Products

Chen, Hasegawa, Schmitt-Ulms, Kawarai, Bohm, Katayama, Gu, Sanjo, Glista, Rogaeva, Wakutani, Pardossi-Piquard, Ruan, Tandon, Checler, Marambaud, Hansen, Westaway, St George-Hyslop, Fraser: "TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity." in: Nature, Vol. 440, Issue 7088, pp. 1208-12, (2006) (PubMed).

Periz, Fortini: "Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2." in: Journal of neuroscience research, Vol. 77, Issue 3, pp. 309-22, (2004) (PubMed).

Selkoe: "The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease." in: Trends in cell biology, Vol. 8, Issue 11, pp. 447-53, (1999) (PubMed).

Synonyms and alternative names related to TMED10

transmembrane p24 trafficking protein 10 L homeolog (tmed10.L), transmembrane p24 trafficking protein 10 (TMED10), transmembrane p24 trafficking protein 10 (Tmed10), transmembrane p24 trafficking protein 10 (tmed10), 1110014C03Rik, fe06g04, p23, P24(DELTA), p24delta1, S31I125, S31III125, Tmp-21-I, tmp21, TMP21, Tmp21, wu:fb98e10, wu:fe06g04, zgc:85681

Protein level used designations for TMED10

  • transmembrane protein tmp21
  • 21 kDa transmembrane trafficking protein
  • 21 kDa transmembrane-trafficking protein
  • p24 family protein delta-1
  • p24delta
  • p24delta1
  • transmembrane emp24 domain-containing protein 10
  • transmembrane protein Tmp21
  • transmembrane trafficking protein
  • integral membrane protein Tmp21-I (p23)
  • transmembrane trafficking protein 21
  • p24 delta 1
  • integral membrane protein p23
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