TMC8 产品
(Transmembrane Channel-Like 8 (TMC8))
Categories
Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs. [provided by RefSeq, Jul 2008].
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Featured TMC8 Categories
Recommended TMC8 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7185610
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (1)
Cat. No.
ABIN3187286
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (1)
Cat. No.
ABIN6265610
Quantity
100 μL
Datasheet
Datasheet
Recommended TMC8 蛋白
Product
Reactivity
Source
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Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322915
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3074205
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3124051
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TMC8 Products
: "Regulation of cellular zinc balance as a potential mechanism of EVER-mediated protection against pathogenesis by cutaneous oncogenic human papillomaviruses." in: The Journal of experimental medicine, Vol. 205, Issue 1, pp. 35-42, (2008) (PubMed).: "Mutations in two adjacent novel genes are associated with epidermodysplasia verruciformis." in: Nature genetics, Vol. 32, Issue 4, pp. 579-81, (2002) (PubMed).
: "Evidence for a nonallelic heterogeneity of epidermodysplasia verruciformis with two susceptibility loci mapped to chromosome regions 2p21-p24 and 17q25." in: The Journal of investigative dermatology, Vol. 114, Issue 6, pp. 1148-53, (2000) (PubMed).
Synonyms and alternative names related to TMC8
transmembrane channel like 8 (TMC8), transmembrane channel-like 8 (Tmc8), transmembrane channel-like gene family 8 (Tmc8), EV2, EVER2, Ever2, EVIN2, mFLJ00400Protein level used designations for TMC8
- transmembrane channel-like 8
- FLJ00400 protein-like
- transmembrane channel-like protein 8-like
- epidermodysplasia verruciformis 2
- epidermodysplasia verruciformis protein 2
- transmembrane channel-like protein 8
- uncharacterized protein LOC688276
- epidermodysplasia verruciformis protein 2 homolog
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