TLR4 蛋白
(Toll-Like Receptor 4 (TLR4))
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| TLR4 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| TLR4 Protein (AA 26-638) (His tag) | 大鼠 | 酵母菌 |
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| TLR4 Protein (AA 1-631) (Fc Tag) | 人 | Eukaryota |
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| TLR4 Protein (AA 661-763) (His-SUMO Tag) | 斑马鱼 | Bacteria |
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| TLR4 Protein (partial) (His tag) | 小鼠 | 酵母菌 |
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| TLR4 蛋白 | 人 | 大肠杆菌（E. Coli） |
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| TLR4 Protein (Fc Tag) | 人 | Mammalian Cells |
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| TLR4 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| TLR4 Protein (His tag) | Cow | 大肠杆菌（E. Coli） |
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Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- 宿主
- 小鼠
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- 宿主
- Cow
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Latest Publications for our TLR4 蛋白
: "CD200 restrains macrophage attack on oligodendrocyte precursors via toll-like receptor 4 downregulation." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, (2015) (PubMed).
: "Analysis of mechanistic pathway models in drug discovery: p38 pathway." in: Biotechnology progress, Vol. 24, Issue 1, pp. 96-109, (2008) (PubMed).
: "Analysis of mechanistic pathway models in drug discovery: p38 pathway." in: Biotechnology progress, Vol. 24, Issue 1, pp. 96-109, (2008) (PubMed).
Aliases for TLR4 蛋白
toll like receptor 4 (TLR4) 蛋白toll-like receptor 4 (Tlr4) 蛋白
toll like receptor 4 (Tlr4) 蛋白
ARMD10 蛋白
CD284 蛋白
Lps 蛋白
Ly87 蛋白
Ran/M1 蛋白
Rasl2-8 蛋白
TLR-4 蛋白
TOLL 蛋白
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