TIGIT 抗体
(T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))
This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity\; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009].
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Latest Publications for our TIGIT 抗体
: "Molecular and functional heterogeneity of IL-10-producing CD4+ T cells. ..." in: Nature communications, Vol. 9, Issue 1, pp. 5457, (2019) (PubMed).: "Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-β and Engagement of CD85j." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 3, pp. 1008-1015, (2018) (PubMed).
: "Suppressive IL-17A+Foxp3+and ex-Th17 IL-17AnegFoxp3+Tregcells are a source of tumour-associated Tregcells." in: Nature communications, Vol. 8, pp. 14649, (2017) (PubMed).
: "HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT)." in: PLoS pathogens, Vol. 12, Issue 1, pp. e1005372, (2016) (PubMed).
: "Binding of the Fap2 protein of Fusobacterium nucleatum to human inhibitory receptor TIGIT protects tumors from immune cell attack. ..." in: Immunity, Vol. 42, Issue 2, pp. 344-55, (2015) (PubMed).
: "Mouse TIGIT inhibits NK-cell cytotoxicity upon interaction with PVR." in: European journal of immunology, Vol. 43, Issue 8, pp. 2138-50, (2013) (PubMed).
Aliases for TIGIT 抗体
T-cell immunoreceptor with Ig and ITIM domains (TIGIT) 抗体T cell immunoreceptor with Ig and ITIM domains (Tigit) 抗体
ENSMUSG00000071552 抗体
RGD1563191 抗体
VSIG9 抗体
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