TIE1 蛋白
(tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].
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TIE1
宿主: 人
宿主: 人细胞
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
Aliases for TIE1 蛋白
tyrosine kinase with immunoglobulin like and EGF like domains 1 (TIE1) 蛋白tyrosine kinase with immunoglobulin-like and EGF-like domains 1 (Tie1) 蛋白
tyrosine-protein kinase receptor Tie-1 (CpipJ_CPIJ018933) 蛋白
endothelium-specific receptor tyrosine kinase 1 (tie1) 蛋白
D430008P04Rik 蛋白
JTK14 蛋白
TIE 蛋白
tie-1 蛋白
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