TIE1 抗体
(tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].
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Latest Publications for our TIE1 抗体
: "Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 17, pp. 4376-4381, (2017) (PubMed).: "Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling." in: Circulation research, Vol. 120, Issue 8, pp. 1276-1288, (2017) (PubMed).
: "Endothelial destabilization by angiopoietin-2 via integrin β1 activation." in: Nature communications, Vol. 6, pp. 5962, (2015) (PubMed).
: "Autocrine role of angiopoietins during megakaryocytic differentiation." in: PLoS ONE, Vol. 7, Issue 7, pp. e39796, (2012) (PubMed).
: "Regulated proteolytic processing of Tie1 modulates ligand responsiveness of the receptor-tyrosine kinase Tie2." in: The Journal of biological chemistry, Vol. 282, Issue 42, pp. 30509-17, (2007) (PubMed).
: "Interaction between Tie receptors modulates angiogenic activity of angiopoietin2 in endothelial progenitor cells." in: Cardiovascular research, Vol. 72, Issue 3, pp. 394-402, (2006) (PubMed).
: "Functions of the activation loop in Csk protein-tyrosine kinase." in: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 24072-7, (2003) (PubMed).
: "Tyrosine phosphorylation of I-kappa B kinase alpha/beta by protein kinase C-dependent c-Src activation is involved in TNF-alpha-induced cyclooxygenase-2 expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 9, pp. 4767-75, (2003) (PubMed).
: "Corneal IL-8 expression following adenovirus infection is mediated by c-Src activation in human corneal fibroblasts." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 12, pp. 6234-43, (2003) (PubMed).
: "Expansion of human SCID-repopulating cells under hypoxic conditions." in: The Journal of clinical investigation, Vol. 112, Issue 1, pp. 126-35, (2003) (PubMed).
Aliases for TIE1 抗体
tyrosine kinase with immunoglobulin like and EGF like domains 1 (TIE1) 抗体tyrosine kinase with immunoglobulin-like and EGF-like domains 1 (Tie1) 抗体
tyrosine-protein kinase receptor Tie-1 (CpipJ_CPIJ018933) 抗体
endothelium-specific receptor tyrosine kinase 1 (tie1) 抗体
D430008P04Rik 抗体
JTK14 抗体
TIE 抗体
tie-1 抗体
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