TIE1 抗体 (AA 851-900)
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北京 101111
Quick Overview for TIE1 抗体 (AA 851-900) (ABIN1451751)
抗原
See all TIE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 851-900
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原理
- Tie-1 Antibody
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特异性
- Tie-1 Polyclonal Antibody detects endogenous levels of Tie-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human TIE1. AA range:851-900
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亚型
- IgG
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应用备注
- IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
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别名
- TIE1
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背景
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Synonyms: TIE1, TIE, Tyrosine-protein kinase receptor Tie-1
Background: This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
Gene Name: TIE1
Protein Name: Tyrosine-protein kinase receptor Tie-1
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分子量
- 125 kDa
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基因ID
- 7075
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OMIM
- 600222
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UniProt
- P35590
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途径
- RTK signaling
抗原
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